General Method for Synthesis of Bipyridines: Palladium Catalyzed Cross-coupling Reaction of Trimethylstannylpyridines with Bromopyridines

Article abstract of DOI:10.1055/s-1986-31705

Trimethylstannylpyridines 1 were treated with bromopyridines 2 in the presence of catalytic amount of tetrakis(triphenylphosphine)palladium to give the corresponding bipyridines 3 in moderate to good yields.Nicotelline (6) was similarly synthesized from 2,4-bis(trimethylstannyl)pyridine (5) and 3-bromopyridine (2b).