Journal of Medicinal Chemistry p. 928 - 931 (1984)
Update date:2022-08-11
Topics:
Christiansen, Robert G.
Neumann, Helmut C.
Salvador, U. Joseph
Bell, Malcolm R.
Schane, H. Phillip
et al.
Several methylated derivatives of trilostane were prepared.Methylation of C-4 or C-4 and C-17 changes this relatively selective adrenal inhibitor to compounds with increased ovarian/placental inhibitory activity with decreased adrenal inhibitory activity.
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