Catalytic Ability of Octopus-Type Calixarene in the Formation of Ethers from Phenols and Alkyl Halides or 1-Chloro-4-nitrobenzene

Article abstract of DOI:10.1246/bcsj.68.3563

The formation of ethers was catalyzed by 5,11,17,23,29,35-hexa-p-t-butyl-37,38,39,40,41,42-hexakis(3,6,9-trioxadecyloxy)calix<6>arene (1).It was found that the calixarene-catalyzed reaction of phenol with benzyl bromide in the presence of KOH in CH2Cl2 yields only the O-alkylated product and this reaction proceeds according to Michaelis-Menten type kinetics.The calixarene 1 also catalyzed the reactions of phenols with dichloromethane and 1-chloro-4-nitrobenzene.