Use of site-specified tritium labelling to confirm the formation of 17-oxosparteine as a minor urinary metabolite of sparteine in man

Article abstract of DOI:10.3109/00498259609052499

The synthesis of [17,17-³H₂]-sparteine and its oral administration has enabled the specific identification of 17-oxosparteine as a minor urinary metabolite (~1% dose) in two healthy male volunteers.

Full text of DOI:10.3109/00498259609052499

Xenobiotica
the fate of foreign compounds in biological systems
ISSN: 0049-8254 (Print) 1366-5928 (Online) Journal homepage: http://www.tandfonline.com/loi/ixen20
Use of site-specified tritium labelling to confirm
the formation of 17-oxosparteine as a minor
urinary metabolite of sparteine in man
J. C. Ritchie, S. C. Mitchell, R. L. Smith & A. Q. Zhang
To cite this article: J. C. Ritchie, S. C. Mitchell, R. L. Smith & A. Q. Zhang (1996) Use of site-
specified tritium labelling to confirm the formation of 17-oxosparteine as a minor urinary
metabolite of sparteine in man, Xenobiotica, 26:9, 977-982
To link to this article: http://dx.doi.org/10.3109/00498259609052499
Published online: 27 Aug 2009.
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Date: 09 November 2015, At: 09:35