Biodegradation p. 119 - 126 (1995)
Update date:2022-08-18
Topics:
Uotila, J. S.
Kitunen, V. H.
Coote, T.
Saastamoinen, T.
Salkinoja-Salonen, M.
Apajalahti, J. H. A.
The actinomycete Rhodococcus chlorophenolicus PCP-1 metabolises pentachlorophenol into ultimate inorganic end products via tetrachloro-p-hydroquinone. This intermediate was further dehalogenated in the cytoplasm requiring reductant in the cell free system. Tetrafluoro-p-hydroquinone and tetrabromo-p-hydroquinone were also dehalogenated. Chlorophenol analogs, thiol blocking agents and molecular oxygen inhibited the activity. The dehalogenating reactions led to 1,2,4-trihydroxybenzene, which was further metabolized into maleic acid.
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