Journal of Organic Chemistry p. 5006 - 5009 (1983)
Update date:2022-08-22
Topics:
Wenkert, Ernest
Orito, Kazuhiko
Simmons, Dana P.
Ardisson, Janick
Kunesch, Nicole
Poisson, Jacques
A synthesis of 20-deethylvincadifformine from methyl nicotinylacetate is described.The reaction scheme involved a fast construction of the pentacyclic nucleus of the Aspidosperma alkaloids and the early incorporation of the 16-carbomethoxy group common to these bases.
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