STRAIGHTFORWARD HOMOCHIRAL SYNTHESIS OF THE LACTONE MOIETY OF MEVINIC ACIDS

Article abstract of DOI:10.1016/0040-4039(93)85028-U

A new straightforward synthesis of the common lactone moiety of mevinic acids is described starting form tri-O-acetyl-D-glucal 2.The key diastereoselective O-glycosidation of 2 with methanol and subsequent methanolysis and tritylation are incorporated in