Journal of Antibiotics p. 245 - 255 (1999)
Update date:2022-08-17
Topics:
Qian-Cutrone, Jingfang
Ueki
Huang, Stella
Mookhtiar, Kasim A.
Ezekiel, Regina
Kalinowski, Steven S.
Brown, Karen S.
Golik, Jerzy
Lowe, Susan
Pirnik, Dolores M.
Hugill, Robert
Veitch, Judy A.
Klohr, Steven E.
Whitney, Jeffrey L.
Manly, Susan P.
During the screening of the natural products for their ability to increase the activity of glucokinase by relieving inhibition by long chain fatty acyl CoA esters (FAC), two novel compounds, glucolipsin A (1) and B (2) were isolated from the butanol extracts of Streptomyces purpurogeniscleroticus WC71634 and Nocardia vaccinii WC65712, respectively. The structures of these two compounds were established by spectroscopic methods and chemical degradation. Glucolipsin A (1) and B (2) relieved the inhibition of glucokinase by FAC with RC50 values of 5.4 and 4.6 μM.
View MoreAstaTech ( Chengdu) BioPharmaceutical Corp.
website:http://www.astabiochem.cn/
Contact:+86-15680585308
Address:SICHUAN CHENGDU
Contact:
Address:ROOM 1715, No#345 Jin Xiang Road, Pudong District
ZUNYI CITY BEI YUAN CHEMICAL CO., LTD
website:http://www.china-beiyuan.com
Contact:+86-851-27751258
Address:Wujiang Building, Xianggang Road, Zunyi City, Guizhou Province, China
Weifang Ocean Trading Co., Ltd.
Contact:+86-536-2081155
Address:Room2606, Yuqing Building, 518#, Yuquan Road, High-tech Development Zone, Weifang City, Shandong Province, China
Nantong Kaixin Pharma Chemical Co.,Ltd.
Contact:86-513-85250786
Address:2-1103 Huachen Mansion, 111 Gongnong Road,Nantong, Jiangsu, China
Doi:10.1039/a808810a
(1999)Doi:10.1016/j.ejmech.2017.04.063
(2017)Doi:10.1002/anie.201709563
(2017)Doi:10.1021/jf9508155
(1996)Doi:10.1142/S1088424616500875
(2016)Doi:10.1021/acschemneuro.7b00454
(2018)