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An improved one-pot synthesis of N-(2,3-dihydrobenzo[1,4]dioxin-2-carbonyl) piperazine - Useful intermediate for anti-hypertensive drug - Doxazosin

DOI: 10.1515/HC.2006.12.5.373

Source and publish data:

Heterocyclic Communications p. 373 - 376 (2006)

Update date:2022-08-11

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Authors:

Ramesh, ChakkaRamesh, Chakka

Reddy, Reguri BuchiReddy, Reguri Buchi

Reddy, Ghanta MaheshReddy, Ghanta Mahesh

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Article abstract of DOI:10.1515/HC.2006.12.5.373

An improved process for the preparation of N-(2,3-dihydrobenzo[1,4]dioxin- 2-carbonyl)piperazine 2 and its hydrochloride from ethyl-2,3-dihydro-1,4- benzodioxin-2-carboxylate 3 and piperazine in a single step has been described. The compound 2 is an important intermediate in the preparation of anti-hypertensive agent, Doxazosin.

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Full text of DOI:10.1515/HC.2006.12.5.373

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Brought to you by | Purdue University Libraries  
Authenticated  
Download Date | 5/24/15 7:23 PM  
Brought to you by | Purdue University Libraries  
Authenticated  
Download Date | 5/24/15 7:23 PM  
Brought to you by | Purdue University Libraries  
Authenticated  
Download Date | 5/24/15 7:23 PM  

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Product name:1-(1,4-Benzodioxane-2-carbonyl)piperazine

Cas No:70918-00-2

70918-00-2

R&D Labs maybe for 70918-00-2

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