Tetrahedron Letters p. 299 - 302 (1981)
Update date:2022-08-30
Topics:
Corey, E. J.
Hashimoto, Shun-ichi
(S)-5-hydroxy-6-trans-8,11,14-cis-eicosatetraenoic acid (5-HETE) (1) and its enantiomer are readily available by a chemical synthesis from arachidonic acid which includes a chromatographic separation of diastereomeric urethanes (3) made from (+/-)-5-HETE methyl ester and the isocyanate 4 derived from dehydroabietylamine.
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(1950)
