Synthesis and Biological Evaluation of N4-Substituted Imidazo- and v-Triazolopyridazine Nucleosides

Article abstract of DOI:10.1021/jm00077a017

The chemical synthesis of certain N⁴-substituted imidazo<4,5-d>pyridazine and v-triazolo<4,5-d>pyridazine nucleosides is described.In both series, the 4-chloro analogues, i.e., 4-chloro-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazo<4,5-d>pyri