Regio- and Stereoselective Samarium Diiodide-Promoted Intermolecular Coupling between Vinyloxiranes and Ketones. Synthesis of 2-Alken-1,5-Diols

Article abstract of DOI:10.1016/0040-4039(95)01416-F

Reduction of vinyloxiranes with SmI2-HMPA at low temperatures in the presence of ketones results in the efficient formation of 2-alken-1,5-diols with predominant or exclusive (E) configuration.In the absence of HMPA higher temperatures are needed for the