Studies on the Synthesis of Chemotherapeutics. 12. Synthesis and Antitumor Activity of N-Phthalidyl-5-fluorouracil Derivatives

DOI: 10.1021/jm00352a024

Source and publish data:

Journal of Medicinal Chemistry p. 1219 - 1222 (1982)

Update date:2022-08-18

Topics:

Authors:

Kametani, Tetsuji

Kigasawa, Kazuo

Hiiragi, Mineharu

Wakisaka, Kikuo

Nakazato, Kikuo

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00352a024

Several N-phthalidyl-5-fluorouracil derivatives were synthesized for preliminary antitumor evaluation.N1-Phthalidyl- and N3-phthalidyl-5-fluorouracils (6 and 10) showed a significant antitumor activity against experimental solid tumors with a good blood l

Full text of DOI:10.1021/jm00352a024

Products guided by the article

Product name:2,4(1H,3H)-Pyrimidinedione, 3-(1,3-dihydro-3-oxo-1-isobenzofuranyl)-5- fluoro-

Cas No:82023-29-8

R&D Labs maybe for 82023-29-8

Wuhan Benjamin Pharmaceutical Chemical Co.,Ltd

Contact:86-27-52341789

Address:Room 1518 B suite, optical valley time square, No 111 Guanshan Road, Hongshan District,Wuhan,Hubei Province,China.
Dalian Synco Chemical Co., Ltd.

Contact:+86-411-83635150

Address:Rm 1004, 24, Tangshan Street, Dalian
QINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.

Contact:+86 532 80861829

Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
Shanghai Pengkai Chemical Co.,Ltd

Contact:+86-21-60526671

Address:No.4226 Duzhuang Rd Minhang District Shanghai China
Chengdu Biopurify Phytochemicals Ltd.

website:http://www.phytopurify.com

Contact:+86-28-82633397

Address:2F,No.11 Building,No.388 Rongtaidadao CNSTP,Wenjiang Zone,Chengdu,Sichuan, China

Relevant to this article

Solid-state rearrangement of sandwich-type polyoxometalate-dopamine nanohybrid to the nanoflower Keggin polyoxometalate: synthesis, characterization, and catalytic efficiency

Doi:10.1080/00958972.2020.1753713
(2020)
Syntheses and Crystal Structures of Two Cadmium Methanetetrabenzoates Featured by Open Framework and Infinite Layers

Doi:10.1002/zaac.201900089
(2019)
Amino acids and peptides. X. Phosphorus in organic synthesis. V. On the mechanism for the peptide synthesis by diphenyl phosphorazidate

Doi:10.1248/cpb.22.855
(1974)
Titanium amido- and imido-complexes supported by a tridentate pyrrolyl ligand: Syntheses, characterisation and catalytic activities

Doi:10.3184/174751912X13324293828161
(2012)
Synthesis and thermal properties of salts comprising cationic bis(oxazoline)-Au^III complexes and fluorinated anions

Doi:10.1016/j.poly.2016.04.012
(2016)
Iridoids from Fraxinus excelsior with adipocyte differentiation-inhibitory and PPARα activation activity

Doi:10.1021/np9003118
(2010)

Article Doi