An improved procedure for the synthesis of chiral 2-aza-bicyclo[2.2.1]heptane

Article abstract of DOI:10.1080/00397919608003651

Grieco's protocol for the synthesis of 2-aza-bicyclo[2.2.1]heptane is modified and adapted for large scale preparation. The optical purity of the material is readily upgraded by purification through a chiral salt.

Full text of DOI:10.1080/00397919608003651

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Synthetic Communications:
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Synthetic Organic Chemistry
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An Improved Procedure for
the Synthesis of Chiral 2-Aza-
Bicyclo[2.2.1]heptane
Charles K.F. Chiu a
a Pfizer Inc. Central Research, Department
of Process R&D , Eastern Point Road, Groton,
Connecticut, 06340, U.S.A.
Published online: 21 Aug 2006.
To cite this article: Charles K.F. Chiu (1996) An Improved Procedure for the
Synthesis of Chiral 2-Aza-Bicyclo[2.2.1]heptane, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry,
26:3, 577-584, DOI: 10.1080/00397919608003651
To link to this article: http://dx.doi.org/10.1080/00397919608003651
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