Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

GLYCIDOL
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

GLYCIDOL

 EINECS 209-128-3
CAS No. 556-52-5 Density 1.179 g/cm3
PSA 32.76000 LogP -0.62250
Solubility soluble in water Melting Point -54 °C
Formula C3H6O2 Boiling Point 162.358 °C at 760 mmHg
Molecular Weight 74.0794 Flash Point 81.111 °C
Transport Information UN 2810 6.1/PG 3 Appearance colourless liquid
Safety 53-45 Risk Codes 45-60-21/22-23-36/37/38-68
Molecular Structure Molecular Structure of 556-52-5 (Glycidol) Hazard Symbols ToxicT
Synonyms

1-Propanol,2,3-epoxy- (7CI,8CI);Glycidol (6CI);Oxiranemethanol (9CI);(RS)-Glycidol;1,2-Epoxy-3-hydroxypropane;2,3-Epoxy-1-propanol;2-(Hydroxymethyl)oxirane;3-Hydroxypropylene oxide;Allyl alcohol oxide;Epihydrin alcohol;Epiol OH;Glycidyl alcohol;NSC 46096;Oxiran-2-ylmethanol;Racemic glycidol;dl-Glycidol;

Article Data 168

GLYCIDOL Synthetic route

107-18-6

allyl alcohol

556-52-5

oxiranyl-methanol

Conditions
ConditionsYield
With tert.-butylhydroperoxide; bis(acetylacetonate)oxovanadium In chlorobenzene at 80℃; for 5h;100%
With sodium persulfate; water at 20℃; for 12h; Reagent/catalyst;100%
With tetrabutylphosphonium peroxotantalate; dihydrogen peroxide In water at 0℃; for 5.5h; Schlenk technique; chemoselective reaction;100%
96-24-2

3-monochloro-1,2-propanediol

556-52-5

oxiranyl-methanol

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water at -5 - 15℃; for 6h; Large scale;98.5%
With sodium hydroxide In water at 18 - 36℃; under 18.7519 Torr; Temperature; Pressure; Concentration; Industrial scale;97.92%
With sodium methylate In methanol at 0 - 15℃; under 2100.21 - 2325.23 Torr; for 0.833333h; Pressure; Temperature;93.76%
931-40-8

4-hydroxymethyl-1,3-dioxolan-2-one

556-52-5

oxiranyl-methanol

Conditions
ConditionsYield
With zinc(II) nitrate; 1-butyl-3-methylimidazolium nitrate at 175℃; under 20.027 Torr; for 2.5h;98.2%
With zinc-lanthanum mixed oxides at 180℃; under 375.038 Torr; Reagent/catalyst;76.22%
With sodium sulfate at 140 - 180℃; for 3h; Green chemistry;33%
67-56-1

methanol

DMTr-glycidol

A

556-52-5

oxiranyl-methanol

B

125016-87-7

bis(4-methoxyphenyl)phenylmethyl methyl ether

Conditions
ConditionsYield
With lithium tetrafluoroborate In dichloromethane at 20℃; for 0.25h; deprotection;A 92%
B n/a
56-81-5

glycerol

616-38-6

carbonic acid dimethyl ester

A

931-40-8

4-hydroxymethyl-1,3-dioxolan-2-one

B

556-52-5

oxiranyl-methanol

Conditions
ConditionsYield
With 30 wt.% KF/γ-Al2O3 at 80℃; for 1.5h; Catalytic behavior; Reagent/catalyst;A 91.3%
B n/a
With fluorinated Mg-Al hydrotalcite derived basic catalyst at 110℃; for 3h; Reagent/catalyst;A 80.5%
B 10.8%
With Mg/Zr/Sr mixed oxide at 90℃; for 1.5h; Catalytic behavior; Temperature; Concentration; Reagent/catalyst;A 56%
B 40%
371-62-0

2-fluoroethanol

2932-58-3

2-fluoro-2-phenylethanol

A

108788-73-4

trans-3-chloroallyl 2,3-epoxypropyl ether

B

128367-32-8

2-(2-Fluoro-2-phenyl-ethoxymethyl)-oxirane

C

556-52-5

oxiranyl-methanol

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate at 25℃; for 24h; Yields of byproduct given;A n/a
B 75%
C n/a
371-62-0

2-fluoroethanol

14365-32-3

trans-2-fluorocyclohexanol

128920-99-0

2-((1S,2S)-2-Fluoro-cyclohexyloxymethyl)-oxirane

B

108788-73-4

trans-3-chloroallyl 2,3-epoxypropyl ether

C

556-52-5

oxiranyl-methanol

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate at 25℃; for 24h; Yields of byproduct given;A 65%
B n/a
C n/a
931-40-8

4-hydroxymethyl-1,3-dioxolan-2-one

A

14236-12-5

2,5-Bis(hydroxymethyl)-1,4-dioxane

B

2,6-bis(hydroxymethyl)-1,4-dioxane

C

1416557-67-9

3-(oxrian-2-yloxy)propane-1,2-diol

D

556-52-5

oxiranyl-methanol

Conditions
ConditionsYield
With sodium chloride at 175℃; under 20.027 Torr; for 0.75h;A n/a
B n/a
C n/a
D 62%
56-81-5

glycerol

A

5464-28-8

1,3-dioxolane-4-methanol

B

4740-78-7

glycerol formal

C

79-14-1

glycolic Acid

D

623-50-7

ethyl 2-hydroxyacetate

E

627-82-7

diglycerol

F

556-52-5

oxiranyl-methanol

G

116-09-6

hydroxy-2-propanone

H

107-02-8

acrolein

Conditions
ConditionsYield
With pretreated aluminium vanadium phosphate In water at 280℃; under 760.051 Torr; Catalytic behavior; Activation energy; Reagent/catalyst; Temperature;A n/a
B n/a
C n/a
D n/a
E n/a
F n/a
G n/a
H 62%
...Expand
56-81-5

glycerol

616-38-6

carbonic acid dimethyl ester

A

931-40-8

4-hydroxymethyl-1,3-dioxolan-2-one

B

76913-29-6

methyl ((2-oxo-1,3-dioxolan-4-yl)methyl)carbonate

C

556-52-5

oxiranyl-methanol

Conditions
ConditionsYield
With potassium fluoride at 80℃; for 1.5h; Catalytic behavior; Reagent/catalyst;A 58.4%
B n/a
C n/a
With tetrabutylammomium bromide at 160℃; under 8250.83 Torr; for 0.05h; Flow reactor;

GLYCIDOL Chemical Properties

Name:Glycidol
Synonyms:2,3-Epoxy-1-propanol; 3-Hydroxy-1,2-epoxypropane
Molecular Structure:  
Molecular Formula:C3H6O2
Molecular Weight:74.08
EINECS:209-128-3
Density:1.1143 g/cm3
Melting point:-54 °C
Boiling point:167 °C (dec.)
Glycidol is an organic compound containing epoxide and alcohol functional groups. It is a clear, slightly viscous liquid .

GLYCIDOL Uses

1.Glycidol is used as a stabilizer for natural oils and vinyl polymers and as a demulsifier.
2.Used in surface coatings, pharmaceuticals, chemical synthesis, and as a gelation agent in solid propellants etc.
3.As a chemical intermediate in the synthesis of glycerol,  esters,amines and glycidyl ethers,.

GLYCIDOL Toxicity Data With Reference

1.   

skn-rbt 558 mg/3D MOD

   AMIHAB    AMA Archives of Industrial Health. 14 (1956),250.
2.   

mmo-klp 200 µmol/L

   MUREAV    Mutation Research. 89 (1981),269.
3.   

cyt-hmn:lym 400 µmol/L

   MUREAV    Mutation Research. 91 (1981),243.
4.   

orl-rat LD50:420 mg/kg

   FCTXAV    Food and Cosmetics Toxicology. 19 (1981),347.
5.   

ihl-rat LC50:580 ppm/8H

   AMIHAB    AMA Archives of Industrial Health. 14 (1956),250.
6.   

ipr-rat LD50:200 mg/kg

   FCTXAV    Food and Cosmetics Toxicology. 19 (1981),347.
7.   

orl-mus LD50:431 mg/kg

   GTPZAB    Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 24 (3)(1980),42.
8.   

ihl-mus LC50:450 ppm/4H

   AMIHAB    AMA Archives of Industrial Health. 14 (1956),250.
9.   

ipr-mus LDLo:500 mg/kg

   PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 35 (1936),98.
10.   

skn-rbt LD50:1980 mg/kg

   AMIHAB    AMA Archives of Industrial Health. 14 (1956),250.

GLYCIDOL Consensus Reports

NTP 10th Report on Carcinogens. Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

GLYCIDOL Safety Profile

Confirmed carcinogen with carcinogenic data reported. Poison by intraperitoneal route. Moderately toxic by ingestion, inhalation, and skin contact. Experimental teratogenic and reproductive effects. A skin irritant. Human mutation data reported. Animal experiments suggest somewhat lower toxicity than for related epoxy compounds. Readily absorbed through the skin. Causes nervous excitation followed by depression. Explodes when heated or in the presence of strong acids, bases, metals (e.g., copper, zinc), and metal salts (e.g., aluminum chloride, iron(III) chloride, tin(IV) chloride). When heated to decomposition it emits acrid smoke and fumes. See also DIGLYCIDYL ETHER.

GLYCIDOL Standards and Recommendations

OSHA PEL: TWA 25 ppm
ACGIH TLV: TWA 2 ppm; Animal Carcinogen
DFG MAK: 50 ppm (150 mg/m3)

GLYCIDOL Analytical Methods

For occupational chemical analysis use NIOSH: Glycidol, 1608.
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 556-52-5