2-Hydroxyethyl formate

Base Information

Chemical Name:2-Hydroxyethyl formate
CAS No.:628-35-3
Molecular Formula:C3H6 O3
Molecular Weight:90.0788
Hs Code.:
European Community (EC) Number:211-038-4
NSC Number:3770
UNII:H8FJC27WY2
DSSTox Substance ID:DTXSID00862322
Nikkaji Number:J521E
Mol file:628-35-3.mol

Synonyms:1,2-ethanediol monoformate;ethylene glycol monoformate

Suppliers and Price of 2-Hydroxyethyl formate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
2-Hydroxyethylformate
1g
$ 445.00

Total 49 raw suppliers

Chemical Property of 2-Hydroxyethyl formate

Chemical Property:

Vapor Pressure:0.36mmHg at 25°C
Refractive Index:1.404
Boiling Point:175.1°C at 760 mmHg
PKA:13.94±0.10(Predicted)
Flash Point:77.8°C
PSA：46.53000
Density:1.136g/cm³
LogP:-0.21240
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Acetone (Slightly), Methanol (Slightly)
XLogP3:-0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:90.031694049
Heavy Atom Count:6
Complexity:35

Purity/Quality:

99.9% ^*data from raw suppliers

2-Hydroxyethylformate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(COC=O)O
Uses Ethylene Glycol is one of the UV irradiation products of 1,4-dioxane in wastewater; Also, it is derived from 1,3-Dioxolane (D486800), which is an intermediate for the preparation of Acyclovir (A192400). Also, 1,3-Dioxolane is used in the synthesis of new Vandetanib (V097100) analogs.

Technology Process of 2-Hydroxyethyl formate

There total 45 articles about 2-Hydroxyethyl formate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 646-06-0
1,3-DIOXOLANE

: 96-49-1
[1,3]-dioxolan-2-one

: 628-35-3
ethylene glycol monoformate

Guidance literature:: With oxygen; CoCl₂; In 1,2-dimethoxyethane; at 60 ℃; for 24h;

Reference yield: 60.0%

: 75-21-8,99932-75-9
oxirane

: 124-38-9,18923-20-1
carbon dioxide

: 628-35-3
ethylene glycol monoformate

: 107-21-1
ethylene glycol

Guidance literature:: With 1-Methylpyrrolidine; 1-methyl-pyrrolidin-2-one; hydrogen; dodecacarbonyl-triangulo-triruthenium; at 140 ℃; for 15h; under 60800 Torr;
DOI:10.1039/c39950001489

Reference yield: 43.0%

: 110-80-5
2-ethoxy-ethanol

: 628-35-3
ethylene glycol monoformate

: 22056-82-2
ethoxyacetaldehyde

: 542-59-6
2-hydroxyethyl acetate

: 109-94-4
formic acid ethyl ester

Guidance literature:: With air; methyl nitrite; nitrogen(II) oxide; at 23.85 ℃; for 2h; under 750 Torr; Further byproducts given; UV-irradiation;
DOI:10.1021/es960348n