Preclinical Development

Medicinal chemistry Structure-Activity Relationship (SAR) Analysis Chemical Synthesis In vitro Testing Biological Assays Structure-Activity Relationship (SAR) Studies Clinical Trials In Vivo Testing Medicinal Chemistry Optimization Clinical Development Post-Marketing Surveillance In Vivo Studies Lead Optimization Formulation Development Regulatory Approval In Vitro Assays Toxicity and Safety Assessment Lead Compound Identification Pharmacokinetic Studies Dose-Response Studies Cell-Based Assays Target Identification and Validation Compound Design Synthesis of Compounds Safety and Toxicity Studies Safety and Toxicology Studies Optimization and Lead Selection Structural Elucidation Cytotoxicity Assays Mechanism of Action Studies In Vivo Efficacy Selectivity Profiling Compound Characterization In Vitro Screening