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50-69-1

Basic Information
CAS No.: 50-69-1
Name: D-Ribose
Article Data: 126
Molecular Structure:
Molecular Structure of 50-69-1 (D-Ribose)
Formula: C5H10O5
Molecular Weight: 150.131
Synonyms: alpha-D-ribose;(2R,3R,4R,5R)-oxane-2,3,4,5-tetrol;(3R,4R,5R)-5-(hydroxymethyl)oxolane-2,3,4-triol;(2R,3R,4R)-2,3,4,5-tetrahydroxypentanal;(2R,3R,4R,5R)-5-(hydroxymethyl)oxolane-2,3,4-triol;Ribo-2,3,4,5-tetrahydroxyvaleraldehyde, D-;D-(-)-Ribose;(2S,3R,4R,5R)-5-(hydroxymethyl)oxolane-2,3,4-triol;Ribose, D-;alpha-D-ribose-5;beta-D-Ribopyranose;Benzoyl Stavudine;
EINECS: 200-059-4
Density: 1.681 g/cm3
Melting Point: 95 °C
Boiling Point: 375.4 °C at 760 mmHg
Flash Point: 180.8 °C
Solubility: 0.1 g/mL in water
Appearance: white powder
Hazard Symbols: IrritantXi
Risk Codes: 36/38
Safety: 24/25-37/39-26
PSA: 97.99000
LogP: -2.73970
Synthetic route
51246-99-2

1,5-Anhydro-2,3-O-isopropylidene-β-D-ribofuranose

50-69-1

D-ribose

Conditions
ConditionsYield
With trifluoroacetic acid at 20℃;90%
Conditions
ConditionsYield
With K 10 clay In methanol; water at 50℃; for 72h;75%
10323-20-3

D-Arabinose

50-69-1

D-ribose

Conditions
ConditionsYield
With molybdic acid In water for 0.05h; Bilik reaction; microwave irradiation;30%
With borax In water at 69.84℃; for 1h; Kinetics; pH-value; stereospecific reaction;
With HNbMoO6 In water at 119.84℃; for 3h; Reagent/catalyst;
With caesium modified hydrated phosphomolybdic acid supported on activated carbon In water at 59.84℃; for 0.5h; Catalytic behavior;
110-86-1

pyridine

488-84-6

D-ribulose

A

10323-20-3

D-Arabinose

B

50-69-1

D-ribose

110-86-1

pyridine

551-84-8

xylulose

A

58-86-6

D-xylose

B

10323-20-3

D-Arabinose

C

50-69-1

D-ribose

75-52-5

nitromethane

124-41-4

sodium methylate

583-50-6

D-erythrose

50-69-1

D-ribose

Conditions
ConditionsYield
With methanol Eintragen einer wss.Loesung des Reaktionsprodukts in wss.Schwefelsaeure bei -20grad;
67006-18-2

O2-methanesulfonyl-D-arabinose

50-69-1

D-ribose

Conditions
ConditionsYield
With barium dihydroxide; water
642-98-8

D-ribonic acid

50-69-1

D-ribose

Conditions
ConditionsYield
With sodium amalgam
30571-54-1

2,3,4,5-tetra-O-acetyl-aldehydo-D-ribose

50-69-1

D-ribose

Conditions
ConditionsYield
With barium dihydroxide; water
13111-79-0

D-glycero-D-manno-[2]octulose

546-67-8

lead(IV) tetraacetate

64-19-7

acetic acid

50-69-1

D-ribose

Conditions
ConditionsYield
und Erwaermen des Reaktionsprodukts mit Wasser;
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Consensus Reports

Ribose, primarily occurring as D-ribose, is an organic compound that occurs widely in nature. Ribose is an aldopentose, that is a monosaccharide containing five CARBON atoms that, in its acyclic form, has an aldehyde functional group at one end. Typically, this species exists in the cyclic form, as depicted in the upper right. It was first reported in 1891 by Emil Fischer. It comprises the backbone of RNA, a biopolymer that is the basis of genetic transcription. It is related to deoxyribose, as found in DNA, by the removal of one hydroxy group. Once phosphorylated, ribose can become a subunit of ATP, NADH, and several other compounds that are critical to metabolism.

Specification

The IUPAC name of D-Ribose is (3R,4S,5R)-5-(hydroxymethyl)oxolane-2,3,4-triol. With the CAS registry number 50-69-1, it is also named as Ribo-2,3,4,5-tetrahydroxyvaleraldehyde, D-. The product's categories are Fine Chemical & Intermediates; Sugars, Carbohydrates & Glucosides; Basic Sugars (Mono & Oligosaccharides); Biochemistry; Nucleosides, Nucleotides & Related Reagents; Ribose; Riboses and 2'-Deoxyriboses; Carbohydrates & Derivatives; Alphabetical Listings; Flavors and Fragrances; Q-Z; Biochemicals Found in Plants; Metabolic Pathways; Metabolites and Cofactors on the Metabolic Pathways Chart, and the other registry numbers are 58-91-3; 6915-40-8; 93781-19-2. Besides, it is white powder, which should be stored in closed and cool place at 2-8 °C. In addition, its molecular formula is C5H10O5 and molecular weight is 150.13.

The other characteristics of this product can be summarized as: (1)EINECS: 200-059-4; (2)ACD/LogP: -1.47; (3)# of Rule of 5 Violations: 0; (4)ACD/LogD (pH 5.5): -1.47; (5)ACD/LogD (pH 7.4): -1.47; (6)ACD/BCF (pH 5.5): 1; (7)ACD/BCF (pH 7.4): 1; (8)ACD/KOC (pH 5.5): 3.77; (9)ACD/KOC (pH 7.4): 3.77; (10)#H bond acceptors: 5; (11)#H bond donors: 4; (12)#Freely Rotating Bonds: 5; (13)Index of Refraction: 1.612; (14)Molar Refractivity: 31.05 cm3; (15)Molar Volume: 89.2 cm3; (16)Surface Tension: 78.7 dyne/cm; (17)Density: 1.681 g/cm3; (18)Flash Point: 180.8 °C; (19)Melting Point: 95 °C; (20)Water Solubility: 1.00E+06 mg/L at 25 °C; (21)Enthalpy of Vaporization: 72.06 kJ/mol; (22)Boiling Point: 375.4 °C at 760 mmHg; (23)Vapour Pressure: 3.6E-07 mmHg at 25 °C.

Preparation of Uses D-Ribose: first, please ferment D-glucose. And then you would obtain this chemical by the separation and purification of the resultant. Additionally, this chemical comprises the backbone of RNA, a biopolymer that is the basis of genetic transcription. It is a useful biochemical reagent, pharmaceutical intermediate used in the pharmaceutical industry. Moreover, it can be used as sweetener and flavoring in the food industry. It also can be used as growth promoting agent of crops and feed additive.

When you are using this chemical, please be cautious about it as the following: it is irritating to eyes and skin. In case of contact with eyes, please rinse immediately with plenty of water and seek medical advice. And you should wear gloves and eye/face protection to avoid contact with skin and eyes.

People can use the following data to convert to the molecule structure.
(1)SMILES: O[C@@H]1[C@H](OC(O)[C@@H]1O)CO
(2)InChI: InChI=1/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5?/m1/s1
(3)InChIKey: HMFHBZSHGGEWLO-SOOFDHNKBV

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