5769-13-1

Basic information

• Product Name: trans-4-phenylcyclohexan-1-ol
• Synonyms: trans-4-phenylcyclohexan-1-ol;trans-4-Phenylcyclohexanol;(1α)-4β-Phenylcyclohexanol;(1α,4β)-4-Phenylcyclohexanol;YVVUSIMLVPJXMY-HAQNSBGRSA-N;Cyclohexanol, 4-phenyl-, trans-
• CAS NO: 5769-13-1
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25484
• EINECS: 227-295-0
• Mol File: 5769-13-1.mol
• Article Data: 87

Chemical Properties

• Boiling Point: 295.8°Cat760mmHg
• Flash Point: 113.3°C
• Appearance: /
• Density: 1.051g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: -20°C Freezer
• Solubility: DCM, Ethyl Acetate
• CAS DataBase Reference: trans-4-phenylcyclohexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: trans-4-phenylcyclohexan-1-ol(5769-13-1)
• EPA Substance Registry System: trans-4-phenylcyclohexan-1-ol(5769-13-1)

Safety Data

• Hazardous Substances Data: 5769-13-1(Hazardous Substances Data)

Usage

Uses

trans-4-Phenylcyclohexanol is an intermediate in the synthesis of Atovaquone derivatives (A793500).

InChI:InChI=1/C12H16O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-5,11-13H,6-9H2/t11-,12-

Upstream product

• 92-69-3 4-Phenylphenol 
• 7335-12-8 cis-4-phenylcyclohexanol 
• 64-19-7 acetic acid 
• 827-52-1 1-phenyl-1-cyclohexane 
• 64-17-5 ethanol 
• 4894-75-1 1-phenyl-4-cyclohexanone 
• 67-56-1 methanol 
• 5769-13-1 4-phenyl-cyclohexanol 
• 1093198-53-8 C₂₈H₂₆O₃ 
• 29538-77-0 trans-4-hydroxycyclohexyl chloride 
• 100-59-4 phenylmagnesium chloride 
• 40504-25-4 4-Phenyl-cyclohexylamine; hydrochloride 
• 30086-03-4 C₂₀H₂₄N₂O₄S 
• 5445-95-4 trans-4-phenylcyclohexyl acetate 

Downstream Products

• 4894-75-1 1-phenyl-4-cyclohexanone 
• 4994-16-5 4-phenylcyclohexene 
• 19992-45-1 cis-4-phenylcyclohexylamine 
• 5437-46-7 trans-4-phenylcyclohexanol 
• 180295-25-4 trans-2-(4-Phenylcyclohexyloxy)tetrahydropyran 
• 250293-45-9 4-Phenylcyclohexanone N-phenylhydrazone 
• 95157-05-4 4-phenyl-cyclohexanone-(2,4-dinitro-phenylhydrazone) 
• 42367-12-4 cis-4-phenyl-1-bromocyclohexane 
• 5445-95-4 O-acetyl-4-phenylcyclohexanol 
• 51171-72-3 4-phenylcyclohex-2-en-1-one 
• 1093198-53-8 C₂₈H₂₆O₃ 
• 199383-82-9 4-phenyl-1-cyclohexen-1-ol acetate 

Relevant articles and documents

Pincerlike molybdenum complex and preparation method thereof, catalytic composition and application thereof, and alcohol preparation method

The invention discloses a clamp-type molybdenum complex, a preparation method, a corresponding catalyst composition and application. The method comprises the steps: obtaining 9 molybdenum complexes with different structures through coordination reaction of 2-(substituent ethyl)-(5, 6, 7, 8-tetrahydroquinolyl) amine and a corresponding carbonyl molybdenum metal precursor; and catalyzing a ketone compound transfer hydrogenation reaction through a molybdenum complex to generate 40 alcohol compounds. The preparation method of the molybdenum complex is simple, high in yield and good in stability. For a transfer hydrogenation reaction of ketone, the molybdenum-based catalytic system has high catalytic activity and small molybdenum loading capacity, is used for production of aromatic and aliphatic alcohols, and has the advantages of simple method, small environmental pollution and high yield.

PNO ligand containing planar chiral ferrocene and application thereof

The invention discloses a PNO ligand containing planar chiral ferrocene and application thereof. The PNO ligand containing planar chiral ferrocene is a planar chiral ferrocene-containing and phenol-containing PNO ligand as shown in a general formula (I) or (II) which is described in the specification, or a planar chiral ferrocene-containing and aryl-phosphoric-acid-containingPNO ligand containing as shown in a general formula (III) or (IV) which is described in the specification, or a planar chiral ferrocene-containing and carbon-chiral-phenol-containingPNO ligand as shown in a general formula (V) or (VI) which is described in the specification. The invention provides tridentate PNO ligands and processes for their complexation with transition metal salts or transition metal complexes; the introduction of salicylaldehyde and derivatives thereof, which are simple and easy to obtain, enables the ligands to have a bifunctionalization effect, and -OH in a formed catalyst has stronger acidity and is beneficial to combination with N/O in polar double bonds. Therefore, due to the bifunctionalization effect of the catalyst, the interaction between the catalyst and a substrate can be greatly improved, so a reaction can obtain higher catalytic activity and stereoselectivity.

Trans-Selective and Switchable Arene Hydrogenation of Phenol Derivatives

A trans-selective arene hydrogenation of abundant phenol derivatives catalyzed by a commercially available heterogeneous palladium catalyst is reported. The described method tolerates a variety of functional groups and provides access to a broad scope of trans-configurated cyclohexanols as potential building blocks for life sciences and beyond in a one-step procedure. The transformation is strategically important because arene hydrogenation preferentially delivers the opposite cis-isomers. The diastereoselectivity of the phenol hydrogenation can be switched to the cis-isomers by employing rhodium-based catalysts. Moreover, a protocol for the chemoselective hydrogenation of phenols to cyclohexanones was developed.