6711-48-4Relevant articles and documents
Controllable synthesis of bis[3-(dimethylamino)propyl]amine over Cr and Co double-doped Cu/Γ-Al2O3
Lin, Chenhui,Li, Jiayi,Guo, Haotian,Wu, Xingchun,Wang, Bowei,Yan, Xilong
, p. 64 - 69 (2018)
The continuous synthesis of bis[3-(dimethylamino)propyl]amine (BPA) by hydrogenation of 3-(dimethylamino)-propionitrile (PN) in the presence of 3-(N,N-dimethylamino)propylamine (PA) over copper-based catalysts was investigated. It was found that Cu-Crsub
Selective synthesis of N,N-bis(3-dimethylaminopropyl)amine over Pd/γ-Al2O3
Lin, Chenhui,Wang, Bowei,Guo, Haotian,Chen, Ligong,Yan, Xilong
, p. 391 - 396 (2018/02/21)
The synthesis of N,N-bis(3-dimethylaminopropyl)amine (BPA) from 3-(dimethylamino)-propionitrile (PN) and 3-(N,N-dimethylamino)propylamine (PA) over Pd/γ-Al2O3 in autoclaves was investigated. A series of Pd catalysts were prepared by different methods and characterized by XRD, TEM, and N2 adsorption–desorption. It was found that their activities were obviously affected by calcination temperature and reducing agent. Among them, the catalyst calcined at 500°C and reduced with NaBH4 exhibited the best performance in this reaction. It was possibly attributed to the better dispersion of palladium particles on γ-Al2O3. Furthermore, reaction parameters were also optimized. Under optimal conditions (PN/PA molar radio 1:1, toluene as solvent), BPA was obtained in 87.9% yield with 95.6% conversion over the above catalyst. Meanwhile, split of PN was observed. A probable mechanism of retro-Michael reaction was also proposed.
METHOD FOR INCREASING THE SPACE-TIME YIELD IN A PROCESS USED FOR THE PRODUCTION OF A SYMMETRIC SECONDARY AMINE
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Page/Page column 13-15, (2008/06/13)
Disclosed is a method for increasing the space-time yield in a process that is used for producing a symmetric secondary amine by reacting a primary amine in the presence of hydrogen and a catalyst at a temperature ranging between 50 and 250 °C and an absolute pressure ranging from 5 to 350 bar. According to the inventive method, the absolute pressure is lowered while the temperature is maintained at the same level.