87861-04-9

Upstream product

• 593-56-6 N-methoxylamine hydrochloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 105-13-5 4-Methoxybenzyl alcohol 
• 3717-21-3 p-methoxyl benzaldoxime 
• 74-88-4 methyl iodide 
• 3717-22-4 (Z)-para-methoxybenzaldehyde oxime 
• 77-78-1 dimethyl sulfate 
• 124-41-4 sodium methylate 
• 140463-02-1 (E)-O-methyl-4-methoxybenzohydroximoyl bromide 
• 7647-01-0 hydrogenchloride 
• 70286-37-2 4-methoxy-benzaldehyde-(O-methyl-seqtrans-oxime ) 
• 7553-56-2 iodine 
• 140462-99-3 (Z)-O-methyl-4-methoxybenzohydroximoyl bromide 
• 3717-21-3 (E)-4-methoxybenzaldoxime 

Downstream Products

• 1671-76-7 p-Methoxyvalerophenon 
• 22920-61-2 (rac)-4-methoxy-N-(1-phenylpropyl)benzenamine 
• 150562-30-4 4-methoxy-N-(1-phenylbut-3-enyl)aniline 
• 6709-42-8 N-(4-methoxyphenyl)-1,1-diphenylmethylamine 
• 132554-75-7 N-(4-methoxyphenyl)-α-butylbenzenemethaneamine 
• 126522-56-3 4-methoxy-N-(1-phenylethyl)aniline 
• 6265-92-5 2-(4-methoxy-phenyl)-benzothiazole 
• 70286-37-2 4-methoxy-benzaldehyde-(O-methyl-seqtrans-oxime ) 
• 91222-74-1 (z)-1-amino-1-(p-methoxyphenyl)-2-(2-pyridyl)ethene 
• 91222-70-7 trans-2-(p-methoxyphenyl)-3-(2-pyridyl)aziridine 
• 874-90-8 4-methoxybenzonitrile 
• 22265-37-8 4-methoxybenzamidine 

Relevant academic research and scientific papers

Cyclic Hydroxamic Acid Analogues of Bacterial Siderophores as Iron-Complexing Agents prepared through the Castagnoli–Cushman Reaction of Unprotected Oximes

The first application of multicomponent chemistry (the Castagnoli–Cushman reaction) toward the convenient one-step preparation of cyclic hydroxamic acids is described. Cyclic hydroxamic acids are close analogues of bacterial siderophores (iron-binding com

One-pot synthesis of alternating peptides exploiting a new polymerization technique based on Ugi's 4CC reaction

We developed a one-pot synthetic technique for alternating peptides. Central to this technique is a new, catalyst-free polymerization based on Ugi's 4CC reaction. The treatment of imines with the ambident molecules bearing both an isocyanide and a carboxylic acid afforded alternating peptides.

Solid-phase synthesis of benzothiazoles using an alkoxyamine linker

An alkoxyamine linker was applied for the solid-phase synthesis of benzothiazoles. The substrate was anchored by aldoxime linkage and products were cleaved from the solid-support by aldoxime-imine exchange coupled with air-oxidation under the weakly acidi

Tandem oxidation processes: The direct conversion of activated alcohols into oximes; synthesis of citaldoxime

The direct conversion of primary alcohols into oximes is reported using manganese dioxide and alkoxylamines/hydroxylamine as their hydrochloride salts or supported on Amberlyst 15. This transformation has been applied to a range of benzylic, allylic and propargylic alcohols and utilised to prepare the natural product citaldoxime.

Stereoselective Synthesis of trans-2-Aryl-3-(2-pyridyl)aziridines from an α-Silyl Carbanion

Five para-substituted benzaldehyde oxime O-methyl ethers (3) reacted with 2-(trimethylsilylmethyl)pyridine (1) in the presence of lithium di-isopropylamide (LDA) in tetrahydrofuran to give the corresponding trans-2-aryl-3-(2-pyridyl)aziridines (4) in high yield (80, 85, 60, 58, and 74percent, respectively), with small amounts of (Z)-1-amino-1-aryl-2-(2-pyridyl)ethenes (5), and N',N'-di-isopropylbenzamidines (7) as byproducts.The yields of compounds (4) and (5) and their ratio were considerably influenced by experimental conditions (especially molar ratio and the addition method of the reactants).When treated with LDA, compounds (3) were quantitatively converted into benzonitriles, which reacted with anion (2) to give enamines (5) after elimination of a trimethylsilyl group from the corresponding N-trimethylsilyl derivatives, or with additional LDA to give the benzamidine (7); aziridines (4) were not transformed into enamines (5) by the action of LDA.On the basis of these results, a reaction mechanism has been discussed for the formation of compounds (4).