950-35-6

Basic information

• Product Name: DIMETHYL-P-NITROPHENYLPHOSPHATE
• Synonyms: O,O-DIMETHYL O-(4-NITROPHENYL) PHOSPHATE;PARAOXON-METHYL;BAY 11678;bay11678;Desmethylnitrophos;Dimethyl paraoxon;dimethyl-4-nitrophenylphosphate;dimethylparaoxon
• CAS NO: 950-35-6
• Molecular Formula: C₈H₁₀NO₆P
• Molecular Weight: 247.14
• Mol File: 950-35-6.mol
• Article Data: 13

Chemical Properties

• Melting Point: 0-4 °C
• Boiling Point: 315 °C at 760 mmHg
• Flash Point: 100 °C
• Appearance: /
• Density: 1.383 g/cm3
• Vapor Pressure: 0.000829mmHg at 25°C
• Refractive Index: n20/D 1.523
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• BRN: 1884904
• CAS DataBase Reference: DIMETHYL-P-NITROPHENYLPHOSPHATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL-P-NITROPHENYLPHOSPHATE(950-35-6)
• EPA Substance Registry System: DIMETHYL-P-NITROPHENYLPHOSPHATE(950-35-6)

Safety Data

• Hazard Codes: T+
• Statements: 28
• Safety Statements: 28-36/37-45
• RIDADR: 3018
• WGK Germany: 3
• RTECS: TC5250000
• HazardClass: 6.1(a)
• PackingGroup: I
• Hazardous Substances Data: 950-35-6(Hazardous Substances Data)

Usage

Uses

Methylparaoxon is used in esterase detoxication of acetylcholinesterase inhibitor pesticides using human liver samples in vitro.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 6061, 1992 DOI: 10.1016/S0040-4039(00)60006-0

InChI:InChI=1/C8H10NO6P/c1-13-16(12,14-2)15-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

Upstream product

• 67-56-1 methanol 
• 777-52-6 1-dichlorophosphoryloxy-4-nitro-benzene 
• 28341-54-0 4-(4-nitrophenoxy)butanoic acid 
• 813-77-4 Dimethyl chlorophosphate 
• 3871-20-3 tris(p-nitrophenyl)phosphate 
• 124-41-4 sodium methylate 
• 298-00-0 parathion-methyl 
• 100-02-7 4-nitro-phenol 
• 799-87-1 bis(p-nitrophenyl) methyl phosphate 
• 677-24-7 methyl dichlorophosphoridate 
• 124391-82-8 Dicyclohexyl-amine; compound with 4-nitro-phenol 
• 868-85-9 Dimethyl phosphite 

Downstream Products

• 512-56-1 trimethyl phosphite 
• 100-02-7 4-nitro-phenol 
• 5954-50-7 phosphorofluoridic acid dimethyl ester 
• 14609-74-6 p-nitrophenolate 
• 813-78-5 dimethylphosphoric acid 
• 10463-05-5 dimethyl ethylphosphonate 
• 51-28-5 2,4-Dinitrophenol 
• 15930-83-3 methyl (4-nitrophenyl)phosphate 
• 812-00-0 methylphosphate 
• 10337-69-6 phosphoric acid methyl ester 4-nitro-phenyl ester; tetramethylammonium salt 
• 7351-83-9 dimethyl phosphate anion 

Relevant articles and documents

Kinetic-spectrophotometric determination of methyl parathion in water and vegetable samples

A new selective and sensitive kinetic method has been developed for spectrophotometric determination of methyl parathion based on its inhibitory effect on the redox reaction between bromate and hydrochloric acid. The decolorization of neutral red by the r

Synthesis, characterization and photocatalytic activity of Ag-TiO2 nanoparticulate film

Ag-TiO2 nanoparticulate film was synthesized by dip coating followed by adsorption and photoreduction in UVA light, characterized by transmission electron microscopy, scanning electron microscopy, energy dispersive analysis of X-rays, glancing angle X-ray diffractometry and UV-Vis absorption spectrophotometry techniques. The data indicated the presence of TiO2 particles of anatase phase of size varying from 5-15 nm, Ag nanoparticles of size varying from 10-20 nm, and also indicated the added visible light activity in Ag-TiO2 nanoparticle films. Photocatalytic degradation of methyl parathion (O,O-dimethyl O-(4-nitrophenyl) phosphorothioate), a well known pesticide in aqueous solution was studied using Ag-TiO2 nanoparticulate film and the data was compared with TiO2 nanoparticulate film. Photocatalytic degradation reactions demonstrated pseudo first order behaviour. Methyl parathion was found to be degraded initially to paraoxon which further was degraded to p-nitrophenol, trimethyl ester of phosphoric acid, trimethyl ester of phosphothioic acid, and finally to phosphate ion. Minute amounts of carbon dioxide and acetaldehyde were also detected. This journal is

Kinetic study on the interactions of cyclodextrins with organic phosphates and thiophosphates

α-Cyclodextrin (α-CD) and 6-O-α-D-glucopyranosyl-β- cyclodextrin (G1-β-CD) affected the rates of phenol release from a few dimethyl(nitrophenyl) phosphates and the corresponding thiophosphates in aqueous alkaline solutions. Curvefitting analysis of change