Representative Structures of Antifungal Triazoles and Their Catalytic Enantioselective Synthesis

June 27, 2024

• Title:       

  Representative Structures of Antifungal Triazoles  and Their Catalytic Enantioselective Synthesis

• Image Source:

  Asymmetric Catalytic Epoxidation of Terminal Enones for the Synthesis of Triazole Antifungal Agents

• Mark:

  Scheme 1

• Associated context:

  The third generation of triazole antifungal agents, such as isavuconazole, efinaconazole, albaconazole, and others  (Scheme 1), have advanced properties related to safety, proper pharmacokinetics, and activity spectrum.