Benzylated β-cyclodextrin-aldehyde and its reaction with organometallic reagents

July 18, 2024

• Title:       

  Benzylated β-cyclodextrin-aldehyde and its reaction with organometallic reagents

• Image Source:

  The grignard reaction of cyclodextrin-6-aldehydes revisited: A study of the stereoselectivity upon addition of organometallic reagents to aldehydes and ketones

• Mark:

  Figure 1

• Associated context:

  From the resulting alcohols, aldehydes, such as 1 (Figure 1), can readily be obtained from oxidation by Dess–Martin periodane (DMP) or Swern conditions. These are potentially important building blocks for artificial enzymes or molecular machines since C–C bond formation at the oxidized position can be achieved.