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Starting from a different synthetic approach

July 19, 2024

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    Starting from a different synthetic approach

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    Synthesis and antiplatelet activity of ethyl 4-(1-benzyl-1H-indazol-3-yl)benzoate (YD-3) derivatives

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    Scheme 3

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    Starting from a different synthetic approach, shown in  Scheme 3, compound 30 (YD-3) was first hydrolyzed,  with 10% NaOH (CAS 1310-73-2), into a carboxylic acid (60) which was converted into an acid chloride (61) by treatment with SOCl2 (CAS 7719-09-7).

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