Poly(cytidylic acid) and poly(adenylic acid) analogues: synthesis and catalytic activity for hydrolysis of dinucleotides and nucleic acids
-
Add time:09/02/2019 Source:sciencedirect.com
Poly(cytidylic acid) and poly(adenylic acid) analogues, resembling closely the structures of the natural polymers, were synthesized by the alternating cyclocopolymerization of a nucleoside derivative and acrylic anhydride, and subsequent hydrolysis. The polymers catalyzed the cleavage of dinuleotides and nucleic acids (DNA and RNA). Poly(cytidylic acid) and poly(adenylic acid) analogues accelerated the hydrolysis of GpG and TpT, respectively, faster than other dinucleotides due to the base pairing.
We also recommend Trading Suppliers and Manufacturers of 5'-Cytidylic acid, 2'-O-Methyl- (cas 18422-43-0). Pls Click Website Link as below: cas 18422-43-0 suppliers
Prev:Poly(5-fluorocytidylic acid)
Next:Oligonucleotides containing modified bases. I. Inhibition of DNA and RNA polymerases by partially thiolated oligocytidylic acids) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Studies on soluble ribonucleic acid of rabbit liver III. Preparation and properties of rabbit-liver soluble RNA09/07/2019
- Stereochemistry of nucleic acid constituents: I. Refinement of the structure of cytidylic acid b‡09/06/2019
- Nutrient media for plant-parasitic nematodes: VI. Nucleic acids content and nucleotide synthesis in Aphelenchoides rutgersi☆09/05/2019
- Preparation and properties of some methylated polycytidylic acids†09/04/2019
- Oligonucleotides containing modified bases. I. Inhibition of DNA and RNA polymerases by partially thiolated oligocytidylic acids09/03/2019
- Poly(5-fluorocytidylic acid)09/01/2019
- Chapter Two - The Role of Nucleic Acid Sensing in Controlling Microbial and Autoimmune Disorders08/31/2019
- Chapter 6 - Nucleic Acids08/30/2019
