cas 131-56-6, 2,4-Dihydroxybenzophenone | Articles data

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Efficient microwave-assisted direct C-benzoylation of phenols and naphthols with benzoic acid catalyzed by bismuth triflate under solvent-free or ionic liquid conditions
An efficient and simple route for the synthesis of ortho-hydroxyaryl ketones has been developed. The microwave-assisted direct C-benzoylation of phenols and naphthols in the presence of metal triflates afforded the corresponding ortho-hydroxyaryl ketones in moderate to excellent yields. Bismuth triflate showed the best catalytic performance compared to other metal triflates. The protocol has advantages including short reaction times, high chemoselectivity towards C-acylation, and simple work-up. Additionally, bismuth triflate can be easily recovered and reused several times without significant loss of catalytic performance.
Tran, Phuong Hoang,Phung, Huy Quang,Duong, Minh Nhat,Pham-Tran, Nguyen-Nguyen
p. 1558 - 1563
(2017)
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Novel process for preparing sun-screening agent 2-hydroxy-4-n-octyloxy benzophenone
The invention discloses a novel process for preparing a sun-screening agent 2-hydroxy-4-n-octyloxy benzophenone. According to the process, 2,4-dihydroxy benzophenone is prepared, and 2,4-dihydroxy benzophenone and 1-chloro-n-octane are used as raw materials, wherein the prepared 2,4-dihydroxy benzophenone is simple in method, has no need of posttreatment and can be directly used as a reaction rawmaterial for subsequent reaction, and the energy consumption is reduced from the source; 1-chloro-n-octane is taken as an alkylation reagent, inorganic base is taken as a catalyst, solvents are addedfor reaction, and the yield of the obtained product 2-hydroxy-4-octyloxybenzophenone is high and can reach 90% or above. According to the method, the raw material cost is reduced, the problem of industrial wastewater at present is solved, in addition, the whole process is mild in condition, few in three wastes, high in yield and good in product quality, the use requirements of the cosmetic industry are met, the technological process is simple to operate and easy to realize, the intermediate reaction process is simple and easy to control, and industrial production can be realized.
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Paragraph 0092-0096

(2021/02/06)

Selective Oxidation of Alkylarenes to the Aromatic Ketones or Benzaldehydes with Water
Here a palladium-catalyzed oxidation method for converting alkylarenes into the aromatic ketones or benzaldehydes with water as the only oxygen donor is reported. This C-H bond oxidation functionalization does not require other oxidants and hydrogen accep
Du, Jihong,Duan, Baogen,Liu, Kun,Liu, Renhua,Yu, Feifei,Yuan, Yongkun,Zhang, Chenyang,Zhang, Jin
supporting information

(2022/02/09)

Novel method for preparing intermediate of sun-screening agent, namely 2-hydroxy-4-methoxybenzophenone
The invention provides a synthesis method for 2,4-dihydroxy benzophenone. The method synthesizes the 2,4-dihydroxy benzophenone by using benzoic acid as an acylating agent in the presence of a catalyst. According to the invention, the benzoic acid with low cost is used as the acylation agent, so a large amount of acidic phenolic wastewater is prevented from being generated on the premise of keeping a high conversion rate, and the environmental burden and the post-treatment cost are greatly reduced. A solid acid catalyst adopted in the method is high in reaction selectivity, can absorb by-product water, is recyclable, has mild recycling treatment condition, and is practicable to operate; an obtained product is high in purity; the conversion rate of raw materials is high; a mother liquor hasfew impurities and can be directly recycled; and industrial production can be achieved easily.
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Paragraph 0064-0078

(2020/05/11)

A SUNSCREEN FORMULATION
Disclosed herein are the synthesis of new classes of sunscreen agents, the usage of such sunscreen agents in sunscreen formulations aiming at reduction of sunscreen agents' skin penetration, and a formulation technology using existing sunscreen agents aiming at reduction of sunscreen agents's kin penetration, therefore improving the bio-safety of the sunscreen products.
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Paragraph 0045-0046; 0049-0050

(2020/06/10)

Clean production method of 2,4-dihydroxy benzophenone
The invention discloses a clean production method of 2,4-dihydroxy benzophenone, wherein the method comprises the steps: by using trichlorotoluene and resorcinol as initial raw materials, reacting ina water/ethanol system to generate 2,4-dihydroxy benzophenone, and concentrating, alkalizing, decolorizing and acidifying a mother solution to implement zero discharge of wastewater. According to themethod, cheap and easily available trichlorotoluene and resorcinol are used as starting materials, the production method is simple in process, green and environment-friendly, the product yield and purity are relatively high, and the method has a wide industrial application prospect.
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Paragraph 0035-0052

(2021/01/15)

Methylene quinone compound and preparation method thereof, and polymerization inhibitor and application thereof
The invention relates to a methylene quinone compound and a preparation method thereof, and a polymerization inhibitor and application thereof. The methylene quinone compound has a structure as described in the specification; and in the structure, R is an alkyl group with a carbon number of 8 to 22, and t-Bu is a tert-butyl group. The above methylene quinone compound plays a polymerization inhibition role by the double mechanisms of quinone polymerization inhibition and ultraviolet absorption, and has excellent polymerization inhibition effect.
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Paragraph 0083-0087; 0095; 0096; 0104; 0105; 0113; 0114

(2019/11/21)

Preparation method of ultraviolet absorbent UV-9
The invention provides a preparation method of an ultraviolet absorbent UV-9. The preparation method comprises following steps: step 1, water and methanol are added to a reaction kettle firstly, stirring is started, resorcinol is added, heating is performed, then benzotrichloride is dropwise added to the reaction kettle until the reaction is completed, mother liquor is subjected to centrifugal spin-drying, washing is performed until pH is neutral, and a UV-0 crude product is obtained; step 2, the UV-0 crude product, toluene and an acid-binding agent sodium carbonate are added to another reaction kettle, heating reflux is performed until no water drops appear, after cooling is performed, a catalyst PEG-400 is added, dimethyl sulfate is dropwise added, a mixture is heated after addition andsubjected to thermal insulation reaction until the components are reacted completely, water is added for washing, a product is left to stand for layering, organic phase is distilled under reduced pressure to remove an organic solvent methylbenzene, and a UV-9 crude product is obtained; step 3, the organic solvent is added to the UV-9 crude product for recrystallization, and a UV-9 finished productis obtained after centrifugation and drying. The problem of non-uniform color of the UV-9 product is solved, the product yield is increased, and the product cost is reduced.
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Paragraph 0024-0027; 0031-0034; 0038-0041

(2019/02/26)

Method for synthesizing ultraviolet ray absorber UV-0 through solid acid catalysis
The invention provides a method for synthesizing an ultraviolet ray absorber UV-0 through solid acid catalysis. The method comprises the following steps that benzoic acid, resorcinol and phosphotungstic acid are added into a container, heating is conducted in an oil bath to 110-140 DEG C, stirring is conducted for a reaction for 5-24 hours, it is monitored that the reaction is completed through thin layer chromatography, after cooling, toluene is added for dissolving the product, and solid catalyst phosphotungstic acid is subjected to suction filtration and recycled; a residue obtained throughevaporation of a filtrate is recrystallized with methanol/water to obtain pale yellow solid, namely the ultraviolet ray absorber UV-0. By means of the process, the yield of the UV-0 is greater than 96%.
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Paragraph 0021; 0022; 0024

(2018/11/10)

A 2, 4 - dihydroxy benzophenone green synthesis process (by machine translation)
The invention belongs to the field of fine chemicals, discloses a 2, 4 - dihydroxy benzophenone ultraviolet absorbent synthesize new process. The steps are as follows: in a reaction container into the resorcinol of ethanol saturated solution with a certain amount of catalyst BiCl3 Or mixed with 5% (w/w) CeO2 Composite HZSM - 5 zeolite catalyst, in the good stirring under heating is dropped saturated ethanol solution of benzoic anhydride, for 60 - 80 °C reflow reaction after a certain time, stop heating, separating solid material. According to the selected catalyst different follow-up processing, separating the catalyst with the crude product, the crude product of ethanol and mixing the fluid is heavy water of crystallization to obtain the finished product 2, 4 - dihydroxy benzophenone. The invention uses low toxicity flavor raw materials and reagent, using novel catalyst has the advantages of easy separation, easy recycling, the whole reaction of simple process, small pollution to the environment, the synthesis of the 2, 4 - dihydroxy benzophenone purity of 99% or more, can achieve the yield 94% or more. Suitable for use as polyvinyl chloride, polystyrene, epoxy resin, cellulose resin, unsaturated resin, coating, and the synthetic rubber of the light stabilizer. (by machine translation)
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Paragraph 0011; 0026-0032

(2018/04/26)

Natural products as sources of new fungicides (II): antiphytopathogenic activity of 2,4-dihydroxyphenyl ethanone derivatives
A series of 17 simple 1-(2,4-dihydroxyphenyl) ethanones were synthesised, and their structures characterised by 1H, 13C NMR and ESI-MS. Their in vitro antifungal activities were evaluated against five phytopathogenic fungi including Glomerella cingulate, Botrytis cirerea, Fusarium graminearum, Curvularia lunata and Fusarium oxysporum f. sp. vasinfectum by the mycelial growth inhibition assay. Compounds 2g and 2h exhibited broad-spectrum inhibitory activity against the mycelial growth of the tested pathogens with IC50 values in the range of 16-36 g/mL, and in particular being more active to G. cingulate, with IC50 values of 16.50 and 19.25 g/mL, respectively, than the other pathogens. Preliminary SAR indicated that an α,β-unsaturated ketone unit of the alkyl chain of the compounds is the structure requirement for fungicidal action. The results suggested that 2g and 2h may be promising leads in the development of new antifungal agents.
Nandinsuren, Tseden,Shi, Wei,Zhang, An-Ling,Bai, Yu-Bin,Gao, Jin-Ming
supporting information
p. 1166 - 1169
(2016/04/20)

Method for preparing sun-screening agent intermediate 2,4-dyhydroxy benzophenone
The invention discloses a method for preparing sun-screening agent intermediate 2,4-dyhydroxy benzophenone. The method comprises the following steps: taking resorcinol and trichloromethyl benzene as raw materials; performing condensation reaction, thereby acquiring 2,4-dyhydroxy benzophenone; and purifying the solvent after reaction, recycling and reusing. The method has the advantages of simple operation, mild preparation conditions, environmental protection and high quality of the prepared product. The yield is 95%-98%, the purity is 95%-99%, and the content of isomer impurities is 1%-4%.
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Paragraph 0033; 0065-0086

(2017/10/13)

Synthesis of industrially important aromatic and heterocyclic ketones using hierarchical ZSM-5 and Beta zeolites
Hierarchical ZSM-5 and Beta zeolites were investigated in the synthesis of wide range of industrially important aromatic/heterocyclic ketones by Friedel-Crafts acylation and benzoylation reactions. For comparative study, conventional ZSM-5 and Beta, and amorphous mesoporous Al-MCM-41 were investigated. Hierarchical zeolites were prepared by multi-ammonium structure directing agents whereas conventional zeolites were prepared by mono-ammonium structure directing agents. Among the catalysts investigated in this study, hierarchical Beta exhibited the highest reactant conversion in the acylation and benzoylation reactions. In this study, the systematic assessment of the catalytic activity of acid catalysts for wide range of aromatic and heterocyclic compounds is shown under one umbrella. To the best of our knowledge, these reactions over hierarchical zeolites (ZSM-5 and Beta) are reported here for the first time. Structure activity relationship is explained based on the physico-chemical properties, molecular size, reactivity of reactants, and reaction mechanism. Catalysts can be easily recovered and reused with negligible loss in the catalytic activity.
Kore, Rajkumar,Srivastava, Rajendra,Satpati, Biswarup
p. 129 - 141
(2015/09/28)

Synthesis and Aminomethylation of 3-Substituted 6-Hydroxy-1,2-Benzisoxazoles
Oximes of 2,4-dihydroxybenzophenones, 1-(2,4-dihydroxyphenyl)-2-phenylethanones, and 1-(2,4-di-hydroxyphenyl)-2-phenoxyethanones were dehydrated with 1,1'-carbonyldiimidazole, yielding 3-substi-tuted 6-hydroxy-1,2-benzisoxazoles, aminomethylation reactions of which were studied with various reagents.
Frasinyuk
p. 1616 - 1623
(2015/02/19)

Triaryl-substituted schiff bases are high-affinity subtype-selective ligands for the estrogen receptor
We have explored the isoelectronic replacement of the C=C double bond found at the core of many nonsteroidal estrogen ligands with a simple Schiff base (C=N). Di- and triaryl-substituted imine derivatives were conveniently prepared by the condensation of benzophenones with various anilines without the need for phenolic hydroxy protection. Most of these imines demonstrated high affinity for the estrogen receptors, which, in some cases exceeded that of estradiol. In cell-based assays, these imines profiled as ERα agonists but as ERβ antagonists, showing preferential reliance on the N-terminal activation function (AF1), which is more active in ERα. X-ray analysis revealed that the triaryl-imines distort the ligand-binding pocket in a new way: by controlling the separation of helices 3 and 11, which appears to alter the C-terminal AF2 surface that binds transcriptional coactivators. This work suggests that C=N for C=C substitution might be more widely considered as a general strategy for preparing drug analogues.
Liao, Zong-Quan,Dong, Chune,Carlson, Kathryn E.,Srinivasan, Sathish,Nwachukwu, Jerome C.,Chesnut, Robert W.,Sharma, Abhishek,Nettles, Kendall W.,Katzenellenbogen, John A.,Zhou, Hai-Bing
p. 3532 - 3545
(2014/05/20)

Cytotoxicity and DNA binding property of triphenylethylene-coumarin hybrids with two amino side chains
Novel triphenylethylene-coumarin hybrids containing two amino side chains were designed and synthesized. Some of these 3,4-diphenyl coumarins, 7b-c (the double chains at 4-position on 3-,4-phenyl, respectively), and 13b-f (the double chains at 4-position on 3-phenyl and 7-position, respectively), showed a broad-spectrum and good anti-proliferative activity against five tumor cells and low cytotoxicity in osteoblast. UV-vis, fluorescence, and circular dichroism (CD) spectroscopies and thermal denaturation exhibited that compounds 7b (R = piperidinyl), 7e (R = NEt2), and 7f (R = 4-methylpiperazinyl) had significant interactions with Ct-DNA by the intercalative mode of binding. Structure activity relationships (SARs) analysis suggested that the location of the two amino alkyl chains would play an important role both in the compounds against tumor cells proliferation and their interactions with DNA.
Zhao, Lian,Yao, Yuchao,Li, Shuai,Lv, Mengjiao,Chen, Hua,Li, Xiaoliu
p. 900 - 904
(2014/02/14)

Cosmetic compositions
Suggested is a cosmetic compositions comprising (a) a crosspolymer obtained from copolymerisation of at least two different polyols and at least one dicarboxylic acid and (b) at least one fragrance.
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(2014/07/08)

A composition for lightening skin and hair
Suggested is a composition comprising (a) sclareolide and (b1) at least one tyrosinase inhibitor; and/or (b2) at least one sun protection factor; and/or (b3) at least one anti-oxidants; and/or (b4) at least one anti-inflammatory agent; and/or (b5) at least one desquamating agent.
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(2014/10/28)

Arylalkyl ketones, benzophenones, desoxybenzoins and chalcones inhibit TNF-α induced expression of ICAM-1: Structure-activity analysis
The interaction between leukocytes and the vascular endothelial cells (EC) via cellular adhesion molecules plays an important role in the pathogenesis of various inflammatory and autoimmune diseases. Small molecules that block these interactions have been targeted as potential therapeutic agents against acute and chronic inflammatory diseases. In an effort to identify potent intercellular cell adhesion molecule-1 (ICAM-1) inhibitors, a large number of arylalkyl ketones, benzophenones, desoxybenzoins and chalcones and their analogs (54 in total) have been synthesized and screened for their ICAM-1 inhibitory activity. The structure-activity relationship studies of these compounds identified three potent chalcone derivatives and also demonstrated the possible mechanism for their ICAM-1 inhibitory activities. The most active compound was found to be 79. A large number of arylalkyl ketones, benzophenones, desoxybenzoins and chalcones as well as their analogs (54 in total) were synthesized and screened for their ICAM-1 inhibitory activity. The structure-activity relationship studies of these compounds identified three potent chalcone derivatives and also demonstrated a possible mechanism of their ICAM-1 inhibitory activities. The most active compound was found to be 79. Copyright
Kumar, Sarvesh,Reddy L, Chandra Shekhar,Kumar, Yogesh,Kumar, Amit,Singh, Brajendra K.,Kumar, Vineet,Malhotra, Shashwat,Pandey, Mukesh K.,Jain, Rajni,Thimmulappa, Rajesh,Sharma, Sunil K.,Prasad, Ashok K.,Biswal, Shyam,Van Der Eycken, Erik,Depass, Anthony L.,Malhotra, Sanjay V.,Ghosh, Balaram,Parmar, Virinder S.
experimental part
p. 368 - 377
(2012/07/31)

Tf2O-mediated direct and regiospecific para-acylation of phenols with carboxylic acids
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Khodaei,Nazari
experimental part
p. 1784 - 1786
(2011/12/04)

BENZOFURAN AND BENZOTHIOPHENE-2-CARBOXYLIC ACID AMIDE DERIVATIVES
The present invention relates to compounds of formula I wherein X, A and R1 to R4 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.
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Page/Page column 23

(2009/02/11)

Body-care and household products and compositions comprising specific sulfur-containing compounds
Disclosed are stabilized body care products, household products, textiles and fabrics which comprise specific sulfur containing compounds. Dyed products and articles are effectively stabilized against color degradation. The products are for example skin-care products, hair-care products, dentifrices, cosmetics, laundry detergents and fabric softeners, non-detergent based fabric care products, household cleaners and textile-care products.
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(2009/04/24)

Direct acylation of phenol and naphthol derivatives in a mixture of graphite and methanesulfonic acid
Graphite in methanesulfonic acid is used to prepare o-hydroxyketones by direct acylation of phenol and naphthol derivatives with carboxylic acids. Georg Thieme Verlag Stuttgart.
Sharghi, Hashem,Hosseini-Sarvari, Mona,Eskandari, Razieh
p. 2047 - 2052
(2007/10/03)

3,6-Dibenzoxyl-1,2-pyridazine: A new versatile benzoyl transferring agent for NH2, -OH and -SH benzoylations
A newly synthesized 3,6-dibenzoxyl-1,2-pyridazine 3 has been investigated for its potential to transfer the benzoyl group to various organic substrates carrying -NH2, -OH and -SH groups. The benzoyl transfer is fairly general in scope, occurs under convenient conditions and provides good to excellent yields of benzoylated products. Moreover, by choosing proper conditions, it is possible to achieve chemoselective benzoylation in bi-functional molecules. For instance, N-benzoylation of aromatic amines can be selectively accomplished over that of aliphatic amines and vice versa by manipulating reaction conditions. Selective N- or O-benzoylation in aminophenols is also possible. Although, not studied in detail, we final that dibenzoate 3 can also be used to effect C-benzoylation of reactive phenols and ketones, as exemplified by the C-benzoylation of resorcinol and acetophenone, respectively. Dibenzoate 3, besides being a crystalline, easy to handle, solid possesses twice the potential as an acyl carrier compared to the other known acyl carriers. These features make 3 as an attractive choice for many applications pertaining to benzoyl transfer reactions.
Mashraqui, Sabir Hussain,Shivaji, Jadhav Latika
p. 927 - 935
(2007/10/03)

SUNSCREEN COMPOSITIONS
The present invention relates to improved sunscreen compositions, more preferably to improved sunscreen compositions containing at least one sunscreening agent (sunscreen) and a silicone-polyamide copolymer.
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(2008/06/13)

Improvement of Selectivity in the Fries Rearrangement and Direct Acylation Reactions by Means of P2O5/SiO2 Under Microwave Irradiation in Solvent-Free Media
P2O5/SiO2 was found to be an efficient new reagent for the Fries rearrangement of acyloxy benzene or naphthalene derivatives and the direct acylation reactions of phenol and naphthol derivatives with carboxylic acids. The reactions proceeded smoothly in the solid state and are highly selective methods for the preparation of the ortho isomers of hydroxyaryl ketones. Microwave irradiation improved the conversion yield to 85-100 percent and the high ortho-regioselectivity of these reactions provides an efficient and versatile procedure for obtaining o-hydroxyaryl ketones in 47-98 percent yield.
Eshghi, Hossein,Rafie, Mohammad,Gordi, Zinat,Bohloli, Moosa
p. 1258 - 1270
(2007/10/03)

Zinc Mediated Friedel-Crafts Acylation in Solvent-Free Conditions under Microwave Irradiation
Zn powder is found to catalyze the Friedel-Crafts acylation of aromatic compounds with acyl halides efficiently under microwave irradiation in solvent-free conditions. Activated substrates undergo acylation predominantly at the para-position. The Zn powder can be re-used up to six times after simple washing with diethyl ether and dilute HCl.
Paul, Satya,Nanda, Puja,Gupta, Rajive,Loupy, Andre
p. 2877 - 2881
(2007/10/03)

Cleavage of aromatic methyl ethers by chloroaluminate ionic liquid reagents
We have discovered serendipitously that chloroaluminate ionic liquids can cleave aromatic methyl ethers under surprisingly mild conditions. Three ionic liquids, viz. [TMAH]-[Al2Cl7], [BMIM][Al2Cl7], and [EMIM][Al2Cl6I], and aluminum chloride were compared in the selective demethylation of 4,5-dimethoxyindanone at the 4-methoxy-function. The ionic liquids exhibited a remarkably high selectivity (96:4) in comparison with aluminum chloride (70:30). In addition, the reaction time was drastically shortened when the ionic liquids were used. Interestingly, the three ionic liquids displayed the same reactivity in the demethylation of 4,5-dimethoxyindanone. Considering the lower cost and the bulk availability of the precursors of [TMAH][Al2Cl7], we conclude that this is the most attractive ionic liquid from an industrial point of view. To make the large-scale application of [TMAH][Al2Cl7] feasible, we have developed a safe upscalable method for its preparation. Furthermore, the scope of ether cleavage by the ionic liquid reagent [TMAH][Al2Cl7] was investigated and it was found that aromatic methyl-, al- lyl-, and benzyl-ether cleavage is applicable to a variety of heterocyclic compounds. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
Kemperman, Gerardus J.,Roeters, Theodorus A.,Hilberink, Peter W.
p. 1681 - 1686
(2007/10/03)

Hypervalent iodine in synthesis 59: Application of polymeric diaryliodonium salts as aryl transfer reagents in SPOS
Polymeric diaryliodonium salts were employed as aryl transfer reagents in the Pd(II) catalyzed cross-coupling reaction with salicylaldehydes, and could be regenerated and recycled for the same reactions.
Chen,Chen
p. 1175 - 1177
(2007/10/03)

Hypervalent iodine in synthesis XXXIV: Palladium-catalyzed coupling reaction of o-hydroxyarylaldehydes with hypervalent iodonium salts via cleavage of the aldehyde C-H bond
A novel way of preparation for o-hydroxyarylketones with mild conditions and good yields by palladium-catalyzed coupling reaction of o- hydroxyarylaldehydes with hypervalent iodonium salts via the cleavage of the aldehyde C-H bond has been reported.
Xia, Min,Chen, ZhenChu
p. 531 - 536
(2007/10/03)

Alumina in Methanesulfonic Acid (AMA) as a New Efficient Reagent for Direct Acylation of Phenol Derivatives and Fries Rearrangement. A Convenient Synthesis of o-Hydroxyarylketones
Alumina in methanesulfonic acid (AMA) is used to prepare o-hydroxyaryl ketones by acylation of phenol and naphthol derivatives with carboxylic acids and the Fries rearrangement of phenolic esters. Mechanistic studies show that the acylation reaction in AMA occurred through an esterification followed by a Fries rearrangement of the phenolic ester by an intermolecular mechanism.
Sharghi, Hashem,Kaboudin, Babak
p. 2678 - 2695
(2007/10/03)

Method of purifying arylphenones
Hydroxy and alkyloxy benzophenones, also known as arylphenones, are efficiently and economically purified by contacting them with inorganic phosphorous compounds in the presence of a non-polar solvent. Best results are obtained when the arylphenone is then treated with an activated carbon and/or activated clay.
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(2008/06/13)

Novel chemoselective de-esterification of esters of polyacetoxy aromatic acids by lipases
Candida cylindracea lipase (CCL) and porcine pancreatic lipase (PPL) have been used for deacetylation of peracetates of methyl and ethyl esters of six different polyphenolic acids in organic solvents. Exclusive de-esterification of the ester groups derived from the phenolic hydroxy and aliphatic acid over the ester group of the aromatic acid and aliphatic alcohol has been achieved affording the corresponding esters of phenolic acids in as high yields as 90-97%. The results have been corroborated with the mechanism of lipase action.
Parmar, Virinder S.,Kumar, Ajay,Bicht, Kirpal S.,Mukherjee, Shubhasish,Prasad, Ashok K.,Sharma, Sunil K.,Wengel, Jesper,Olsen, Carl E.
p. 2163 - 2176
(2007/10/03)

Synthese von 4-Alkoxy-2-hydroxyphenylketoximen als Metallextraktions-Reagenzien
The C-Acylation (Friedel-Crafts reaction) of resorcinol with aluminium chloride, the monoetherification in 4-position of the resulting 2,4-dihydroxyphenylketones, and the preparation of oximes (8, 9, 10, 11) from this ketones were investigated.The compounds obtained are characterized by elemental analysis, and the i.r., u.v. and 1H-n.m.r. spectra are discussed.Solubility data of some oximes are determined in water, octane and toluene.The extraction properties for copper-(II)-and iron-(III)-ions are measured by isotope methods in relation to the extragent structure, the extraction time and the pH-range.
Beger, J.,Binte, H.-J.,Brunne, L.,Neumann, R.
p. 269 - 277
(2007/10/02)

STUDY IN CROSSOVER FRIES MIGRATION
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Khanna, R. N.,Singh, K. P.,Sharma, Jyotsana
p. 687 - 690
(2007/10/03)

(Trichloromethyl)benzene: A versatile reagent for the preparation of substituted benzophenones
Aromatic and heteroaromatic compounds were benzoylated efficiently with (trichloromethyl)benzene in 1,2-dichloroethane in the presence of aluminium chloride in good yield.
Ayyanger,Lahoti,Srinivasan,Daniel
p. 322 - 324
(2007/10/02)

Preparation of benzophenones
Benzophenones are prepared by condensing benzoic acids and aromatics of the benzene series by means of boron trifluoride in nitrobenzene as reaction medium.
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(2008/06/13)

Light-stable screening cosmetic composition containing bixin combined with a lipid-soluble UV filter and its use for protecting the human epidermis against ultra-violet radiation
The invention relates to a light-stable cosmetic composition for protecting the human epidermis against UV radiation, containing at least 0.0025% by weight of bixin combined with at least 1% by weight of one or more lipid-soluble agents screening UV radiation, chosen from 3-benzylidene-dl-camphor, its derivatives and benzophenone derivatives, in a cosmetically acceptable vehicle comprising at least one fatty phase. The bixin takes the form of an oily extract of annatto containing at least 0.1% by weight of bixin.
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(2008/06/13)

Transparent cosmetic composition that reflects infrared radiation and its use for protecting the human epidermis against infrared radiation
Transparent cosmetic composition that reflects infrared radiation and its use for protecting the human epidermis against infrared radiation. The invention relates to a transparent cosmetic composition comprising, by way of an agent that reflects infrared radiation for protecting the human epidermis, a substance which is dispersible in the cosmetic medium used, possessing a reflectance (R) of infrared radiation equal to at least 45%, and of which a 2% strength dispersion in vaseline possesses an optical transmission in the visible of at least 85%, chosen from a diatom of particle size less than 100 microns, hollow glass microspheres of size less than 100 microns, a bismuth oxychloride of particle size less than 75 microns and zirconium powder covered ceramic microparticles of particle size less than 8 microns. This cosmetic composition can also contain 0.5 to 20% by weight of UV-A, UV-B or broad-band screening agents.
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(2008/06/13)

Radiation-sensitive resin composition
The radiation-sensitive resin composition, containing an alkali-soluble resin, comprises 1,1-bis(4-hydroxyphenol)-1-phenylethane, 1,1,1-tris(4-hydroxyphenyl)ethane or a compound selected from a polyhydroxy compound having the following formula: and quinonediazidesulfonates of the polyhydroxy compound, and the like. The radiation-sensitive resin composition is suitable for use as a positive type photoresist which has such excellent developability as to inhibit effectively the generation of scum in the formation of a photoresist pattern, has high sensitivity and is excellent in heat resistance and remained thickness ratio upon development.
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(2008/06/13)

Production of hydroxy arylophenones
Production of a hydroxy arylophenone by reacting an aromatic carboxylic acid Ar(--CO2 H)p where Ar is an aromatic radical, (--CO2 H) is an aromatic carboxylic acid group, and p is 1 or 2 with an aromatic compound H--Ar'--OH where Ar' is an aromatic radical and --H and --OH are aromatically bound para to each other in a benzenoid ring, in the presence of an alkyl sulphonic acid, particularly methane sulphonic acid, to produce a hydroxy arylophenone of formula Ar(--CO--Ar'--OH)p where the carbonyl and hydroxyl groups are para to each other in the hydroxyl-containing benzenoid ring of Ar'. The production of the hydroxy arylophenone proceeds through the intermediate ester (H--Ar'--O--CO--)p Ar and the production of the hydroxy arylophenone starting from the ester is also claimed.
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(2008/06/13)

High molecular weight piperidine derivatives as UV stabilizers
Substituted high molecular weight hindered spiropiperidine compounds and polymer compositions stabilized by these compounds. The spiropiperidine compounds are prepared by reacting hindered 4-piperidinone hydrochloride with an activated benzene, such as resorcinol, in an acid medium.
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(2008/06/13)

Chemistry of Quinones. Part 6. The Selective Hydrolysis of α-Acetoxyanthraquinones and Related Compounds by Trifluoroacetic Acid Containing Small Amounts of Water
Acetoxy- or benzoyloxy-substituents adjacent to the carbonyl groups of anthraquinone, 1,4-naphthoquinone, naphthacene-5,12-quinone, benzophenone, and methyl benzoate are selectively converted into hydroxy-groups by treatment with trifluoroacetic acid containing small amounts of water.In the absence of water a reversible acidolysis occurs.Water reacts with the acylating agent, thus preventing the reverse reaction.Evidence is presented that the hydrolyses are of the AAC1 type.
Harrison, Charles R.,Hodge, Philip,Khan, Naeem
p. 1592 - 1594
(2007/10/02)