120-07-0Relevant articles and documents
A BODIPY-based fluorescent sensor for the detection of Pt2+ and Pt drugs
Bian, Qingyuan,Kong, Fred Ka-Wai,Leung, Ken Cham-Fai,Ng, Maggie,Tang, Fung-Kit,Tse, Anfernee Kai-Wing,Tse, Yu-Chung,Yam, Vivian Wing-Wah,Zhu, Jiaqian
, p. 2695 - 2698 (2020)
A BODIPY-based fluorescent sensor PS with an NO4S2 podand ligand was studied for the selective detection of Pt2+ over 21 cations as well as selected platinum drugs in aqueous medium. The platinum sensor PS shows 28-fold, 22-fold and 14-fold fluorescence turn-on enhancements to Pt2+, cisplatin and nedaplatin, and was thereby employed to detect platinum drugs in A-549 human lung cancer cells.
Kinetic parameter estimation of solvent-free reactions monitored by 13C NMR spectroscopy, a case study: Mono- and di-(hydroxy)ethylation of aniline with ethylene carbonate
Lucchini, Vittorio,Fabris, Massimo,NoE, Marco,Perosa, Alvise,Selva, Maurizio
, p. 154 - 160 (2011)
The kinetics of solvent-free reactions can be followed in situ by 13C nuclear magnetic resonance (NMR) spectroscopy, provided that the reaction mixture can be maintained liquid at the monitoring temperature. The pros and cons of the technique and the correct translation of the signal intensities into concentrations are discussed. A good model for this investigation is the reaction of ethylene carbonate (1) with aniline (2) at 140°C, two alkylation products of N-mono- and N, N-bis-(2-hydroxy)ethylation of aniline form (compounds 3 and 4, respectively). The overall reaction occurs with heavy volume shrinking, so that the physical as well as the chemical features evolve during the course of the process. The chemical evolution is described by the kinetic constants k1 and k2 of the two N-alkylation steps, the physical evolution by the time-dependent activity coefficients α(t). Two complementary procedures are utilized for the determination of these parameters.
Synthesis of New Bis-1,2,4-Oxadiazoline Derivatives via 1,3-Dipolar Cycloaddition Reaction
Chen, Fei,Zeng, Hua,Liu, Fang-Ming
, p. 1866 - 1870 (2016)
A series of novel bis-oxadiazoline derivatives 4 was synthesized via 1,3-dipolar cycloaddition reaction of bis-aldimines 3, and nitrile oxides generated in situ from various benzohydroximinoyl chlorides in the presence of Et3N. The target products were confirmed by IR,1H-NMR, and mass spectrometry.
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Adkins,Simington
, p. 1687,1688 (1925)
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Synthesis, characterization and properties of NLO dye-containing polyurethane
Moon,Shim,Lee
, p. 91 - 97 (1994)
Polyurethane attached hemicyanine dye with tetraphenylborate anion was synthesized. This polymer was soluble in dimethylformamide and could be processed into thin film by spin coating. The poled polymer film showed a large second-order nonlinear optical coefficient (χ(2) = 4.0×10-7 esu) and good temporal stability.
A water-soluble BODIPY based ‘OFF/ON' fluorescent probe for the detection of Cd2+ ions with high selectivity and sensitivity
Maity, Apurba,Ghosh, Utsav,Giri, Dipanjan,Mukherjee, Devdeep,Maiti, Tapas Kumar,Patra, Sanjib K.
supporting information, p. 2108 - 2117 (2019/02/12)
A water-soluble dilithium salt BODIPY derivative (LiBDP) with appended dicarboxylate pseudo-crown ether [NO4] coordinating sites has been designed, synthesized and characterized successfully for the selective and sensitive recognition of Cd2+ in aqueous media. The chemosensor exhibits a remarkable increase in fluorescence intensity as well as a distinct color change upon the addition of Cd2+ over other environmentally and biologically relevant metal ions in H2O. The fluorometric response of LiBDP is attributed to the metal chelation-enhanced fluorescence (MCHEF) effect which has been confirmed by a strong association constant of 2.57 ± 1.06 × 105 M?1 and Job's plot, indicating 1?:?1 binding stoichiometry between LiBDP and Cd2+. Frontier molecular orbital analysis (obtained from DFT studies) also illustrates the turn-on fluorescence of the probe by blocking photoinduced electron transfer (PET) after coordination to Cd2+. The probe can detect Cd2+ in a competitive environment up to a submicromolar level in a biologically significant pH range. The sensor is proved to be reversible and reusable by the alternative addition of Cd2+ followed by S2?. The OFF/ON/OFF sensing behavior is utilized to construct an INHIBIT molecular logic gate based on the two inputs of Cd2+ and S2? and a fluorescence intensity at 512 nm as an output. The test paper experiment demonstrates the practical utility of LiBDP to monitor Cd2+ in an aqueous sample. Finally, the sensing probe was utilized to monitor Cd2+ in living cells.
A straightforward one-pot synthesis of bioactive: N -aryl oxazolidin-2-ones via a highly efficient Fe3O4@SiO2-supported acetate-based butylimidazolium ionic liquid nanocatalyst under metal- and solvent-free conditions
Gupta, Radhika,Yadav, Manavi,Gaur, Rashmi,Arora, Gunjan,Sharma, Rakesh Kumar
, p. 3801 - 3812 (2017/08/22)
In the present study, we report the fabrication and characterization of novel acetate-based butylimidazolium ionic liquid immobilized silica-coated magnetic nanoparticles (IL-OAc@FSMNP). The synthesized nanocomposite proves its supremacy as an environmentally benign catalyst in the reaction of aniline and its derivatives with ethylene carbonate to form bioactive N-aryl oxazolidin-2-ones under metal-, ligand-, and solvent-free conditions. The catalyst offers excellent assemblies of hydrogen-bond donors and acceptors, which activate the substrates, thereby delivering good-to-excellent product yields with a conversion and selectivity of more than 99%. Additionally, mild reaction conditions, wide substrate scope, effortless catalytic recovery and recyclability of the catalyst up to eight consecutive cycles offer the potential for scale-up in various pharmaceutical applications.
