Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Difluorochloromethane

Related Products

Hot Products

Name

Difluorochloromethane

EINECS 200-871-9
CAS No. 75-45-6 Density 1.277 g/cm3
PSA 0.00000 LogP 1.44780
Solubility slightly soluble in water Melting Point -146 °C
Formula CHClF2 Boiling Point -40.8 °C
Molecular Weight 86.4687 Flash Point N/A
Transport Information UN 1018 Appearance Colourless gas
Safety 23-59 Risk Codes 40-59
Molecular Structure Molecular Structure of 75-45-6 (Methane,chlorodifluoro-) Hazard Symbols FlammableF
Synonyms

Algeon 22;Algofrene 22;Algofrene 6;Arcton 22;Arcton 4;CFC 22;Chlorodifluoromethane;Daiflon 22;Difluoromonochloromethane;Dymel 22;F 22 (halocarbon);FC 22;FC 22 (halocarbon);FKW 22;Flugene22;Forane 22;Freon 22;Frigen 22;Fron 22;HFA 22;Haltron 22;Isceon 22;Isotron 22;Khladon 22;Korfron 22;Propellant 22;Refrigerant R 22;Solkane 22;Ucon 22;

Article Data 92

Difluorochloromethane Synthetic route

chlorodifluoromethyllithium

75-45-6

Chlorodifluoromethane

Conditions
ConditionsYield
With 2,2,2-trifluoroethanol In N,N,N,N,N,N-hexamethylphosphoric triamide decompn. in the presence of CF3CH2OH at reflux temp., 12 h;100%
In N,N,N,N,N,N-hexamethylphosphoric triamide
75-09-2

dichloromethane

7664-41-7

ammonia

A

74-90-8

hydrogen cyanide

B

75-45-6

Chlorodifluoromethane

Conditions
ConditionsYield
nickel In neat (no solvent) steady-state flow reaction over Ni catalyst at 723 K;A 98.3%
B 0.6%
nickel In neat (no solvent) steady-state flow reaction over Ni catalyst at 673 K;A 75.4%
B 1.7%
79-53-8

chloropentafluoroacetone

A

75-45-6

Chlorodifluoromethane

B

354-34-7

trifluoroacetyl fluoride

C

2925-22-6

2,2-difluoroacetyl fluoride

D

152239-89-9

C3HClF6O

Conditions
ConditionsYield
With chlorine monofluoride; cesium fluoride 1.) -140 degC to -75 degC over 6 h, 2.) -75 degC, 2 h; Further byproducts given;A n/a
B n/a
C n/a
D 90%
75-09-2

dichloromethane

7664-41-7

ammonia

A

74-90-8

hydrogen cyanide

B

75-10-5

Difluoromethane

C

75-45-6

Chlorodifluoromethane

D

124-38-9

carbon dioxide

E

201230-82-2

carbon monoxide

Conditions
ConditionsYield
nickel titanate In neat (no solvent) steady-state flow reaction over NiTO3*6H2O catalyst at 773 K, further by-product is CFH3 (yield 0.3 %);A 81.8%
B 0.1%
C 0.6%
D 10.4%
E 6.8%
nickel titanate In neat (no solvent) steady-state flow reaction over NiTO3*6H2O catalyst at 823 K, further by-product is CFH3 (yield 0.4 %);A 66.2%
B 0.2%
C 1.4%
D 12.9%
E 18.8%
With catalyst: Pt/C In neat (no solvent) steady-state flow reaction over Pt/C catalyst at 821 K, a further by-product is CFH3 (yield 0.2 %);A 64.6%
B 0.3%
C 0.2%
D 0.6%
E 0.8%
1895-39-2

sodium chlorodifluoroacetate

75-45-6

Chlorodifluoromethane

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 100℃;68%
75-09-2

dichloromethane

7664-41-7

ammonia

A

74-90-8

hydrogen cyanide

B

593-53-3

Methyl fluoride

C

75-10-5

Difluoromethane

D

75-45-6

Chlorodifluoromethane

E

124-38-9

carbon dioxide

Conditions
ConditionsYield
With catalyst: Pt/C In neat (no solvent) steady-state flow reaction over Pt/C catalyst at 769 K;A 53.4%
B 0.3%
C 0.5%
D 7.6%
E 0.5%
1717-59-5

2,2-difluoro-2-(fluorosulfonyl)acetic acid

1005-30-7

sodium 4-iodo-benzoate

A

75-45-6

Chlorodifluoromethane

B

120608-87-9

4-Iodo-benzoic acid difluoromethyl ester

Conditions
ConditionsYield
With potassium chloride In acetonitrile at 50℃; for 2.5h;A n/a
B 45%
79-38-9

Chlorotrifluoroethylene

152239-89-9

C3HClF6O

A

75-45-6

Chlorodifluoromethane

B

354-34-7

trifluoroacetyl fluoride

C

2925-22-6

2,2-difluoroacetyl fluoride

D

2-(2,2-Dichloro-1,1,2-trifluoro-ethoxy)-1,1,1,2,3,3-hexafluoro-propane

Conditions
ConditionsYield
In trichlorofluoromethane for 18h; -135 degC to 25 degC; Further byproducts given;A n/a
B n/a
C n/a
D 40%
420-49-5

chlorodifluoroiodomethane

potassium hydroxide

A

75-45-6

Chlorodifluoromethane

B

584-08-7

potassium carbonate

Conditions
ConditionsYield
In ethanol decompn. with alc. KOH at 35°C in 48h;;A 24%
B n/a
In ethanol
75-43-4

Dichlorofluoromethane

1188-14-3

Triethylgerman

A

75-10-5

Difluoromethane

B

75-09-2

dichloromethane

C

75-46-7

trifluoromethan

D

75-45-6

Chlorodifluoromethane

E

994-28-5

triethylchlorogermane

Conditions
ConditionsYield
With ACF. Et3GeH at 25℃; for 72h; Schlenk technique; Inert atmosphere;A n/a
B n/a
C 22%
D 16%
E n/a

Difluorochloromethane Chemical Properties

Molecular Formula: CHClF2
Molecular Weight: 86.47
EINECS: 200-871-9 
Index of Refraction: 1.278
Density: 1.277 g/cm3
Melting point: -146 °C
Boiling Point: 155 °C
Water solubility: Slightly soluble
Appearance: Colourless gas
Structure of Difluorochloromethane (CAS NO.75-45-6):
                      
IUPAC Name: Chloro(difluoro)methane
Product Category of Difluorochloromethane (CAS NO.75-45-6): refrigerants;Organics;Refrigerant

Difluorochloromethane Uses

 Difluorochloromethane (CAS NO.75-45-6) is mainly used as mainlyPropellant, fumigant, insecticide. It  was once commonly used as a propellant and in air conditioning applications.

Difluorochloromethane Production

 Difluorochloromethane (CAS NO.75-45-6) can be prepared from Chloroform : HCCl3 + 2HF → HCF2Cl + 2HCl .

Difluorochloromethane Toxicity Data With Reference

1.    

mmo-sat 33 pph/24H-C

    TOLED5    Toxicology Letters. 2 (1978),1.
2.    

mma-sat 33 pph/24H-C

    TOLED5    Toxicology Letters. 2 (1978),1.
3.    

ihl-rat LC50:35 pph/15M

    HUTODJ    Human Toxicology. 1 (1982),239.
4.    

ihl-mus LC50:28 pph/20M

    TXAPA9    Toxicology and Applied Pharmacology. 59 (1981),64.
5.    

ihl-dog LCLo:70 pph

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),363.

Difluorochloromethane Consensus Reports

It is reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Difluorochloromethane Safety Profile

Hazard Codes: FlammableF
Risk Statements: 40-59 
R40:Limited evidence of a carcinogenic effect. 
R59:Dangerous to the ozone layer.
Safety Statements: 23-59 
S23:Do not breathe vapour. 
S59:Refer to manufacturer / supplier for information on recovery / recycling.
Mildly toxic by inhalation. Experimental reproductive effects. Mutation data reported. An asphyxiant in high concentrations. At elevated pressures, 50% mixtures with air are combustible although ignition is difficult. When heated to decomposition it emits toxic fumes of F and Cl.

Difluorochloromethane Standards and Recommendations

OSHA PEL: TWA 1000 ppm
ACGIH TLV: TWA 1000 ppm; Not Classifiable as a Human Carcinogen
DFG MAK: 500 ppm (1800 mg/m3)
DOT Classification:  2.2; Label: Nonflammable Gas

Difluorochloromethane Specification

 Difluorochloromethane , its cas register number is 75-45-6. It also can be called Chlorodifluoromethane ; Fluorocarbon 22 ; Freon R-22 ; and Freon 22 . Difluorochloromethane (CAS NO.75-45-6) is shipped as a liquefied gas under its own vapor pressure, and is noncombustible. Difluorochloromethane can asphyxiate by the displacement of air. Contact with the liquid can cause frostbite.

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields