Chemistry of Heterocyclic Compounds p. 1091 - 1094 (1985)
Update date:2022-07-31
Topics:
Khripak, S. M.
Yakubets, V. I.
Dobosh, A. A.
The acylation of 2-thio-3-R-4-oxo-3,4-dihydrothieno<2,3-d>-pyrimidines by means of benzoyl chloride was studied.Depending on the reaction conditions, it may take place with formation of S-substituted and N-substituted derivatives.The bromination of the sodium salts of thienopyrimidines and their S- and N-substituted derivatives is accompanied by the formation of disulfides, which do not react with electrophilic reagents but react with amines to give 2-amino derivatives of thienopyrimidines.
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