Journal of Organic Chemistry p. 2781 - 2784 (1986)
Update date:2022-07-31
Topics:
Saa, Carlos
Guitian, Enrique
Castedo, Luis
Suau, Rafael
Saa, Jose Manuel
13-Alkyl and 13-aryl substituted 8-oxoprotoberberines were obtained by interamolecular benzyne cycloaddition of isoquinolinopyrrolinediones with arynes.This convergent and highly regioselective reaction has been applied to the synthesis of (+/-)-corydalin
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