Tetrahedron Letters p. 5627 - 5630 (1985)
Update date:2022-08-03
Topics:
Hanessian, Stephen
Murray, Peter J.
Sahoo, Soumya P.
A chiral 4-hydroxymethyl butenolide is used as a template for the stereocontrolled conjugate addition of a C-methyl group.A sequential two-carbon extension and reformation of a lactone with the new side-chain leads to a "replicated" butenolide, which is s
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