AN EFFICIENT AND STEREOCONTROLLED SYNTHESIS OF PLATELET ACTIVATING FACTOR FROM (S)-(-)-MALIC ACID

DOI: 10.1016/S0040-4039(00)98901-9

Source and publish data:

Tetrahedron Letters p. 5195 - 5198 (1985)

Update date:2022-07-30

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Authors:

Tsuri, Tatsuo

Kamata, Susumu

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Article abstract of DOI:10.1016/S0040-4039(00)98901-9

A stereocontrolled synthesis of C₁₆-PAF (11) from (S)-(-)-malic acid (1), employing regioselective hydrogenolytic cleavage of benzylidene acetal derivatives of (S)-1,2,4-butanetriol (2) with borane-tetrahydrofuran complex, is described.

Full text of DOI:10.1016/S0040-4039(00)98901-9

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