European Journal of Medicinal Chemistry p. 316 - 336 (2018)
Update date:2022-08-15
Topics:
Milik, Sandra N.
Abdel-Aziz, Amal Kamal
Lasheen, Deena S.
Serya, Rabah A.T.
Minucci, Saverio
Abouzid, Khaled A.M.
In light of the emergence of resistance against the currently available EGFR inhibitors, our study focuses on tackling this problem through the development of dual EGFR/HER2 inhibitors with improved enzymatic affinities. Guided by the binding mode of the
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