Tetrahedron Letters p. 5947 - 5950 (1985)
Update date:2022-07-29
Topics:
Mori, Miwako
Kimura, Masaya
Uozumi, Yasuhiro
Ban, Yoshio
A one step synthesis of 1,4-benzodiazepines from o-haloanilines and amino acids was achieved by use of palladium catalyzed carbonylation, by which application a synthesis of the model compounds (23a and 23b) of Neothramycin (A and B) was described.An efficient chemoselective reduction of the amide was provided.
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