Tetrahedron Letters p. 1391 - 1394 (1986)
Update date:2022-07-31
Topics:
Naesman, Jan H.
Kopola, Nina
Pensar, Goeran
The tetramethyldiamido phosphate group is described as a novel and tetracoordinated directing group in a reliable and synthetically useful β-lithiation of furan 1.Addition of 1.1 equiv. n-BuLi to 1 and quenching with electrophiles gave 2,3-disubstituted furans 3.In 98-100 percent formic acid 3 is converted to 4 in good overall yield.Thus furyltetramethyldiamido phosphate 1 is a d2-synthon for 2-furanone.
View MoreChemieliva Pharmaceutical Co., Ltd.
website:http://www.chemieliva.com
Contact:+86-23-67770219
Address:99 Longhua Road, Yubei District, 401147, Chongqing, China Email: sales@chemieliva.com Tel:0086-23-67770219 Fax: 0086-23-67770220 Attn: Andy Huang
Hebei DaPeng Pharm & Chem Co., Ltd.
Contact:86-317-7298678,0576-88861898 88861908
Address:West Songmen Village, East Songmen Town, Wuqiao, Cangzhou, Hebei ,China
Hefei Highzone Fine Chemical S&T CO.,LTD
Contact:86-0551-63663560
Address:room 1801 NO. 24 Shuguang RD.
SHANDONG ZHANHUA YONGHAO PHARMACEUTICAL TECH.CO.,LTD
Contact:+86-576-88685096
Address:GENGJU VILLAGE NORTH ONE KILOMETER,ZHANHUA DISTRICT,BINZHOU CITY,SHANDONG PROVINCE,CHINA.
SHANGHAI GILEADER ADVANCE MATERIAL TECHNOLOGY CO.,LTD
website:http://www.tanguitech.com/contact.asp
Contact:+86-021-58692556
Address:No.6 Building,No. 668 Hengan RD Pudong,Shanghai
Doi:10.1016/S0008-6215(00)90210-6
(1986)Doi:10.1055/s-2004-831330
(2004)Doi:10.1016/j.bmcl.2015.09.027
(2015)Doi:10.1021/jacs.5b11796
(2016)Doi:10.1021/jo01281a094
(1967)Doi:10.1134/S1070363213070281
()
