Tetrahedron Letters p. 1391 - 1394 (1986)
Update date:2022-07-31
Topics:
Naesman, Jan H.
Kopola, Nina
Pensar, Goeran
The tetramethyldiamido phosphate group is described as a novel and tetracoordinated directing group in a reliable and synthetically useful β-lithiation of furan 1.Addition of 1.1 equiv. n-BuLi to 1 and quenching with electrophiles gave 2,3-disubstituted furans 3.In 98-100 percent formic acid 3 is converted to 4 in good overall yield.Thus furyltetramethyldiamido phosphate 1 is a d2-synthon for 2-furanone.
View MoreShandong Xinke Petrochemical Co., Ltd.
Contact:+86-546-7277016
Address:Gudao Industrial Park, Hekou District, Dongying, Shandong Province, China
Shandong Jincheng Zhonghua Bio-pharmaceutical Co.,Ltd
Contact:+86-533-5415882
Address:Zichuan Economic Development Zone,Zibo City,Shandong Province,China
Suzhou Sibian Chemical Technology Co., Ltd
website:http://www.sibianpharm.com
Contact:+8618169181984,+8618013186906
Address:Room1404,BuildingA,Jiabao Square No.323 Baodai East Road,Wuzhong District,Suzhou Jiangsu China (215128)
Shenyang Xingzhenghe Chemical Co., Ltd.
Contact:024-23509232
Address:No. 33, Naner Road, Heping Dist.
Contact:+86-10-67147360/67107388
Address:No.18 Guangming Zhongjie, Chongwen District, Beijing, 100061, China
Doi:10.1016/S0008-6215(00)90210-6
(1986)Doi:10.1055/s-2004-831330
(2004)Doi:10.1016/j.bmcl.2015.09.027
(2015)Doi:10.1021/jacs.5b11796
(2016)Doi:10.1021/jo01281a094
(1967)Doi:10.1134/S1070363213070281
()
