Direct isocoumarin synthesis through LDA-promoted addition of acetaldehyde on orsellinate. An abrupt synthesis of 6-hydroxymellein, a fungal phytotoxin

Article abstract of DOI:10.1080/00397919208021540

The LDA-promoted addition of acetaldehyde on orsellinate gives (±) 6-hydroxymellein, a fungal phytotoxin, with a 51% yield.

Full text of DOI:10.1080/00397919208021540

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Direct Isocoumarin Synthesis
Through LDA-Promoted
Addition of Acetaldehyde
on Orsellinate. An Abrupt
Synthesis of 6-Hydroxymellein,
a Fungal Phytotoxin
Michel Barbier a & Michel Devys a
a Institut de Chimie des Substances Naturelles,
CNRS , Avenue de la Terrasse, 91198, Gif sur Yvette,
Cedex, France
Published online: 23 Sep 2006.
To cite this article: Michel Barbier & Michel Devys (1992) Direct Isocoumarin
Synthesis Through LDA-Promoted Addition of Acetaldehyde on Orsellinate. An Abrupt
Synthesis of 6-Hydroxymellein, a Fungal Phytotoxin, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 22:19,
2757-2762, DOI: 10.1080/00397919208021540
To link to this article: http://dx.doi.org/10.1080/00397919208021540
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