Synthesis of 1,1,1-ethanetriacetonitrile, precursor of 6-substituted-4-methyl-2-aminopyridines

Article abstract of DOI:10.1016/S0040-4039(97)10596-2

1,1,1-ethanetriacetonitrile 1a, a new symmetrical tridentate ligand has been prepared from 3-methylpentenedioic acid diethylester. 6-Substituted-4-methyl-2-aminopyridines were obtained through organometallic additions on 1a.