Asymmetric Synthesis of the Both Enantiomers of Tertiary Aryl Homoallyl Alcohols and Diols by Diastereoselective Addition of Allyltrimethylsilane to Chiral α-Keto Imides

Article abstract of DOI:10.1246/cl.1987.341

Both enantiomers of homoallyl-alcohols and -diols are obtained in high enantiomeric excess (91 -> 98 e.e.) by titanium tetrachloride promoted diastereoselective addition of allyltrimethylsilane to chiral α-keto imides.