Tetrahedron Letters p. 97 - 100 (1987)
Update date:2022-08-03
Topics:
Keshava Murthy, K. S.
Hassner, Alfred
Two routes were examined that permit conversion of 4-vinyl-2-azetidinones 7 via intramolecular nitrile oxide-olefin or azide-olefin cycloaddition into tricyclic β-lactams.Stereoselectivity in these cycloadditions as well as further chemoselective transformations of the products were shown to be dependent on the size of the newly formed ring.
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