AN ALTERNATIVE SYNTHESIS OF (1R,2S,3R,4R)-2,3-DIHYDROXY-4-HYDROXYMETHYL-1-CYCLOPENTANAMINE, A SYNTHETIC INTERMEDIATE OF (-)-ARISTEROMYCIN

Article abstract of DOI:10.1016/S0040-4039(00)96196-3

The title compound, an enantiomerically pure carbocyclic portion of the antibiotic (-)-aristeromycin, has been synthesized from D-erythrose.The synthesis involves a transformation of the known carbocyclic analogue of β-L-arabinofuranose to the α-D-ribo fo