Tetrahedron Letters p. 3419 - 3422 (1987)
Update date:2022-08-02
Topics:
Shute, Richard E.
Rich, Daniel H.
A hydroxy-mediated Fmoc/methyl ester double deprotection procedure followed by an improved bis(2-oxo-3-oxazolidinyl)phosphinic chloride (BOP-Cl) cyclisation reaction are reported.This novel methodology was applied to the synthesis of three new HC-toxin analogues.
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