N- tripeptide derivatives as inhibitors of renin

DOI: 10.1016/0223-5234(88)90171-7

Source and publish data:

European Journal of Medicinal Chemistry p. 83 - 86 (1988)

Update date:2022-08-04

Topics:

Authors:

Quirante, Josefina

Johnson, Rodney L.

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Article abstract of DOI:10.1016/0223-5234(88)90171-7

The following N-2(S)-hydroxy-4-methylpentyl derivatives of Gly-Val-Phe-OMe and Leu-Val-Phe-OMe were designed as analogues of the transition state of the renin-angiotensinogen reaction: N-<2(S)-hydroxy-4-methylpentyl> Gly-Val-Phe-OMe 2 and N-<2(S)-hydroxy-

Full text of DOI:10.1016/0223-5234(88)90171-7

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