Optical Resolution of 2-Methylpiperazine by Complex Formation with Optically Active 1-Phenyl-1-(o-chlorophenyl)prop-2-yn-1-ol and 1,6-Diphenyl-1,6-di(o-chlorophenyl)hexa-2,4-diyne-1,6-diol

Article abstract of DOI:10.1246/cl.1988.513

An efficient optical resolution of 2-methylpiperazine was achieved by complex formation with the title host compounds.X-Ray crystal structure of a 1:2 complex of (S)-(+)-piperazine and (R)-(-)-1-phenyl-1-(o-chlorophenyl)prop-2-yn-1-ol was studied.