3-Substituted-γ-butyrolactones from 5-Trimethylsilyl-2-cyclohexenone. Synthesis of (-)-Enterolactone

DOI: 10.1246/cl.1988.805

Source and publish data:

Chemistry Letters p. 805 - 808 (1988)

Update date:2022-08-02

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Authors:

Asaoka, Morio

Fujii, Naoaki

Shima, Kunihisa

Takei, Hisashi

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Article abstract of DOI:10.1246/cl.1988.805

1,4-Adducts of 5-trimethylsilyl-2-cyclohexenone (1) with Grignard reagents were converted to various hexanoate derivatives and γ-butyrolactones.Starting from optically pure 1, (-)-enterolactone (Factor X) was synthesized.

Full text of DOI:10.1246/cl.1988.805

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