2-AZA-1,3-DIENES AS NOVEL PRECURSORS FOR THE SYNTHESIS OF N-UNSUBSTITUTED β-LACTAMS. A THREE STEP SYNTHESIS OF 4-ACETOXY-3-PHENOXY-2-AZETIDINONE

Article abstract of DOI:10.1016/S0040-4039(00)87894-6

2-Aza-1,3-dienes, prepared in excellent yields from aldehydes and readily available allylamine, were utilized to synthesize N-(1-propenyl)-β-lactams.Oxidative cleavage of the N-protecting group produced N-unsubstituted β-lactams. 4-Acetoxy-3-phenoxy-2-aze