THE EFFICIENT SYNTHESIS OF A O-PHOSPHOTYROSINE-CONTAINING PEPTIDE USING MODERN DEPROTECTION METHODS

DOI: 10.1016/0040-4039(88)85301-2

Source and publish data:

Tetrahedron Letters p. 3591 - 3592 (1988)

Update date:2022-07-31

Topics:

Authors:

Kitas, E. A.

Perich, J. W.

Johns, R. B.

Tregear, G. W.

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Article abstract of DOI:10.1016/0040-4039(88)85301-2

The O-phoshpotyrosine-containing peptide Pro-PTyr-Val was prepared in high yield by the incorporation of Boc-Tyr(PO3Me2)-OH in peptide synthesis and the use of TFMSA/TFA/DMS/ m-cresol or 1M TMSBr/TFA/m-cresol for the final peptide deprotection.

Full text of DOI:10.1016/0040-4039(88)85301-2

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