Synthesis of 3'-amino-3'-deoxyadenosine derivatives as potential drugs for the treatment of malaria

Article abstract of DOI:10.1080/15257779508012396

A series of 3'-substituted 3'-amino-3'-deoxyadenosine analogues were synthesized and subsequently tested against the human malaria parasite Plasmodium falciparum in vitro. Several amongst them displayed pronounced antiplasmodial activities.

Full text of DOI:10.1080/15257779508012396

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Synthesis of 3′-Amino-3′-
deoxyadenosine Derivatives as Potential
Drugs for the Treatment of Malaria
Johanna Soenens a , Guido François b , Elfride Van den Eeckhout a &
Piet Herdewijn a
a Department of Medicinal Chemistry, Faculty of Pharmaceutical
Sciences , Universiteit Gent , Harelbekestraat, 72, B-9000, Gent,
Belgium
b Laboratory of Protozoology , Prince Leopold Institute of Tropical
Medicine , Nationalestraat, 155, B-2000, Antwerpen, Belgium
Published online: 16 Feb 2007.
To cite this article: Johanna Soenens , Guido François , Elfride Van den Eeckhout & Piet Herdewijn
(1995) Synthesis of 3′-Amino-3′-deoxyadenosine Derivatives as Potential Drugs for the Treatment of
Malaria, Nucleosides and Nucleotides, 14:3-5, 409-411
To link to this article: http://dx.doi.org/10.1080/15257779508012396
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