Total synthesis and biological assessment of (-)-Exiguolide and analogues

DOI: 10.1002/chem.201003135

Source and publish data:

Chemistry - A European Journal p. 2678 - 2688 (2011)

Update date:2022-09-26

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Authors:

Fuwa, Haruhiko

Suzuki, Takaya

Kubo, Hiroshi

Yamori, Takao

Sasaki, Makoto

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Article abstract of DOI:10.1002/chem.201003135

We describe herein an enantioselective total synthesis of (-)-exiguolide, the natural enantiomer. The methylene bis(tetrahydropyran) substructure was efficiently synthesized by exploiting olefin cross-metathesis for the assembly of readily available acycl

Full text of DOI:10.1002/chem.201003135

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