Synthetic Communications p. 587 - 594 (2010)
Update date:2022-08-04
Topics:
Sun, Wen-Bo
Zhang, Peng
Fan, Jia
Chen, Shao-Hua
Zhang, Zhan-Hui
A simple, efficient, one-pot method has been developed for the synthesis of tetrahydro-4H-chromene derivatives by concurrent reaction of aryl aldehydes, active methylene compounds, and 1,3-cyclohexanedins using a catalytic amount of lithium bromide in aqueous media. The present approach offers several advantages such as shorter reaction times, good yields, low cost, recycling of the catalyst, and simple workup. Copyright Taylor & Francis Group, LLC.
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